Management of bullous pemphigoid: the European Dermatology Forum consensus in collaboration with the European Academy of Dermatology and Venereology

被引:249
作者
Feliciani, C. [1 ]
Joly, P. [2 ]
Jonkman, M. F. [3 ]
Zambruno, G. [4 ]
Zillikens, D. [5 ]
Ioannides, D. [6 ]
Kowalewski, C. [7 ]
Jedlickova, H. [8 ]
Karpati, S. [9 ]
Marinovic, B. [10 ]
Mimouni, D. [11 ]
Uzun, S. [12 ]
Yayli, S. [13 ]
Hertl, M. [14 ]
Borradori, L. [15 ]
机构
[1] Univ Parma, Dept Dermatol, I-43100 Parma, Italy
[2] Univ Rouen, Dept Dermatol, INSERM, U905, Rouen, France
[3] Univ Groningen, Univ Med Ctr Groningen, Dept Dermatol, NL-9713 AV Groningen, Netherlands
[4] IRCCS, Ist Dermopat Immacolata, Lab Mol & Cell Biol, Rome, Italy
[5] Med Univ Lubeck, Dept Dermatol, D-23538 Lubeck, Germany
[6] Aristotle Univ Thessaloniki, Dept Dermatol, GR-54006 Thessaloniki, Greece
[7] Med Univ Warsaw, Dept Dermatol, Warsaw, Poland
[8] Masaryk Univ, Dept Dermatol, Brno, Czech Republic
[9] Semmelweis Univ, Dept Dermatol, H-1085 Budapest, Hungary
[10] Univ Zagreb, Sch Med, Univ Hosp Ctr Zagreb, Dept Dermatol & Venereol, Zagreb 41001, Croatia
[11] Tel Aviv Univ, Dept Dermatol, IL-69978 Tel Aviv, Israel
[12] Akdeniz Univ, Dept Dermatol, TR-07058 Antalya, Turkey
[13] Karadeniz Tech Univ, Dept Dermatol, Trabzon, Turkey
[14] Univ Marburg, Dept Dermatol, Marburg, Germany
[15] Univ Bern, Inselspital, Univ Hosp Bern, Dept Dermatol, CH-3010 Bern, Switzerland
关键词
LINKED-IMMUNOSORBENT-ASSAY; DIRECT IMMUNOFLUORESCENCE; TOPICAL CORTICOSTEROIDS; MYCOPHENOLATE-MOFETIL; PLASMA-EXCHANGE; DIAGNOSIS; MULTICENTER; AZATHIOPRINE; DISEASES; DIFFERENTIATION;
D O I
10.1111/bjd.13717
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients, bullae may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. Our consensus for the treatment of bullous pemphigoid has been developed under the guidance of the European Dermatology Forum in collaboration with the European Academy of Dermatology and Venereology. It summarizes evidence-based and expert-based recommendations.
引用
收藏
页码:867 / 877
页数:11
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