Withanolides from Withania somnifera roots

被引：112

作者：

Misra, Laxminarain ^{[1
]}

Mishra, Priyanka ^{[1
]}

Pandey, Archana ^{[1
]}

Sangwan, Rajender S. ^{[1
]}

Sangwan, Neelam S. ^{[1
]}

Tuli, Rakesh ^{[2
]}

机构：

[1] Cent Inst Med & Aromat Plants, PO CIMAP, Lucknow 226015, Uttar Pradesh, India

[2] Natl Bot Res Inst, Lucknow 226001, Uttar Pradesh, India

来源：

PHYTOCHEMISTRY | 2008年 / 69卷 / 04期

关键词：

Withania somnifera L; solanaceae; Ashwagandha; withanolides; withasteroids;

D O I：

10.1016/j.phytochem.2007.10.024

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new and seven known withanolides along with beta-sitosterol, stigniasterol, beta-sitosterol glucoside, stigniasterol glucoside, alpha + beta glucose were isolated from the roots of Withania somnifera. Among the known compounds, Viscosa lactone B, stigmasterol, stigmasterol glucoside and alpha + beta glucose are being reported from the roots of W. somnifera for the first time. One of the new compounds contained the rare 16 beta-acetoxy-17(20)-ene the other contained unusual 6 alpha-hydroxy-5,7 alpha-epoxy functional groups in the withasteroid skeleton. The structures were elucidated by spectroscopic methods and chemical transformations. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1000 / 1004

页数：5

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