Signaling to the actin cytoskeleton

被引：370

作者：

Schmidt, A ^{[1
]}

Hall, MN ^{[1
]}

机构：

[1] Univ Basel, Biozentrum, Dept Biochem, Basel, Switzerland

来源：

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY | 1998年 / 14卷

关键词：

signal transduction; GTPase; rho; actin; PI kinase;

D O I：

10.1146/annurev.cellbio.14.1.305

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The actin cytoskeleton is a highly dynamic network composed of actin polymers and a large variety of associated proteins. The main functions of the actin cytoskeleton are to mediate cell motility and cell shape changes during the cell cycle and in response to extracellular stimuli, to organize the cytoplasm, and to generate mechanical forces within the cell. The reshaping and functions of the actin cytoskeleton are regulated by signaling pathways. Here we broadly review the actin cytoskeleton and the signaling pathways that regulate it. We place heavy emphasis on the yeast actin cytoskeleton.

引用

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页码：305 / 338

页数：34

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