Use of salt hydrate pairs to control water activity for enzyme catalysis in ionic liquids

被引：57

作者：

Berberich, JA ^{[1
]}

Kaar, JL ^{[1
]}

Russell, AJ ^{[1
]}

机构：

[1] Univ Pittsburgh, McGowan Inst Regenerat Med, Pittsburgh, PA 15219 USA

来源：

BIOTECHNOLOGY PROGRESS | 2003年 / 19卷 / 03期

关键词：

D O I：

10.1021/bp034001h

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Salt hydrate pairs were used to control water activity in the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate. It was shown that salt hydrate pairs behave essentially the same in ionic liquids as they do in organic solvents as long as they do not dissolve. Initial rate-water activity profiles were prepared for the immobilized Candida antarctica lipase catalyzed synthesis of 2-ethylhexyl methacrylate. The ability to use salt hydrate pairs for the control of water activity in ionic liquids should allow for improved comparison of enzyme activity and specificity in ionic liquids and conventional solvents.

引用

页码：1029 / 1032

页数：4

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