Mechanism of Traditional Chinese Medicine in Treating Knee Osteoarthritis

被引：115

作者：

Wang, Mina ^{[1
,2
]}

Liu, Lu ^{[1
,3
]}

Zhang, Claire Shuiqing ^{[4
]}

Liao, Zehuan ^{[5
,6
]}

Jing, Xianghong ^{[3
]}

Fishers, Marc ^{[7
,8
]}

Zhao, Luopeng ^{[1
,9
]}

Xu, Xiaobai ^{[1
]}

Li, Bin ^{[1
]}

机构：

[1] Capital Med Univ, Beijing Key Lab Acupuncture Neuromodulat, Beijing Hosp Tradit Chinese Med, Acupuncture & Moxibust Dept, Beijing, Peoples R China

[2] Beijing Univ Chinese Med, Grad Sch, Beijing 100029, Peoples R China

[3] China Acad Chinese Med Sci, Inst Acupuncture & Moxibust, Beijing, Peoples R China

[4] RMIT Univ, Sch Hlth & Biomed Sci, Melbourne, Vic, Australia

[5] Nanyang Technol Univ, Sch Biol Sci, Singapore 637551, Singapore

[6] Karolinska Inst, Biomedicum, Dept Microbiol Tumor & Cell Biol MTC, SE-17177 Stockholm, Sweden

[7] Beth Israel Deaconess Med Ctr, Dept Neurol, Boston, MA 02215 USA

[8] Harvard Med Sch, Boston, MA 02115 USA

[9] Capital Med Univ, Beijing Inst Tradit Chinese Med, Beijing Hosp Tradit Chinese Med, Beijing, Peoples R China

来源：

JOURNAL OF PAIN RESEARCH | 2020年 / 13卷

基金：

中国博士后科学基金;

关键词：

knee osteoarthritis; acupuncture; moxibustion; herbs; massage; LOW-GRADE INFLAMMATION; RHEUMATOID-ARTHRITIS; EXPRESSION; PROSTAGLANDIN-E2; CHONDROCYTES; CHEMOKINE; TISSUE;

D O I：

10.2147/JPR.S247827

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Knee osteoarthritis (KOA) is a degenerative disease, making a unique contribution to chronic pain, edema, and limited mobility of knee joint. Traditional Chinese Medicine (TCM) is a common complementary therapy for KOA and has been found effective. The aim of this review is to consolidate the current knowledge about the mechanism of four interventions of TCM: acupuncture, moxibustion, herbs, and massage in treating KOA, and how they alleviate symptoms such as pain, swelling, and dysfunction. Furthermore, this review highlights that four therapies have different mechanisms but all of them can manage KOA through inhibiting inflammation, which indicates that alternative therapies should be considered as a viable complementary treatment for pain management in clinical practice.

引用

页码：1421 / 1429

页数：9

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