共 22 条
Human bocavirus infections and co-infections with respiratory syncytial virus and Rotavirus in children with acute respiratory or gastrointestinal disease
被引:15
作者:

Mohammadi, Mehrdad
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机构:
Isfahan Univ Med Sci, Dept Microbiol, Esfahan, Iran Isfahan Univ Med Sci, Dept Microbiol, Esfahan, Iran

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Yazdanpour, Zahra
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h-index: 0
机构:
Razi Vaccines & Serum Res Inst, Karaj, Iran Isfahan Univ Med Sci, Dept Microbiol, Esfahan, Iran
机构:
[1] Isfahan Univ Med Sci, Dept Microbiol, Esfahan, Iran
[2] Shahid Beheshti Univ Med Sci, Mofd Childrens Hosp, Pediat Infect Res Ctr, Tehran, Iran
[3] Razi Vaccines & Serum Res Inst, Karaj, Iran
关键词:
Human bocavirus;
Acute respiratory infections;
Viral infections;
Co-infections;
Gastrointestinal infections;
ACUTE GASTROENTERITIS;
D O I:
10.1007/s42770-019-00150-x
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The objective of this study was to determine the frequency and seasonal distributions of HBoV detections among Iranian children presenting with acute respiratory or gastrointestinal symptoms and to compare infections among children with concomitant respiratory syncytial virus (RSV) and rotavirus (RV) infections. A cross-sectional study at Mofid Children's Hospital in Tehran, Iran, enrolled children < 3 years old presenting with either acute respiratory or gastrointestinal symptoms during the period of 2017-2018. Respiratory or stool specimens collected from each group were initially tested by RT-PCR assays for RSV and RV, respectively, and all specimens were tested for HBoV by PCR assay. Clinical and demographic data were collected and statistically compared. Five hundred respiratory and stool specimens each were tested and 67 (13.4%) and 72 (14.4%) were PCR positive for HBoV, respectively. Of 128 (25.6%) respiratory specimens positive for RSV, 65% were also positive for HBoV (p = 0.019); of 169 (33.8%) stool specimens positive for RV, 62.5% were also positive for HBoV (p = 0.023). Peak circulation of all viruses was during late winter and early spring months (Jan-Mar) in gastrointestinal infections and during winter (Feb-Jan) in respiratory infections. HBoV is commonly detected among Iranian children presenting with acute respiratory or gastrointestinal symptoms and is often present as co-infections with RSV and RV, respectively.
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页码:45 / 51
页数:7
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