Synovial sarcoma mimicking a thoracic dumbell schwannoma- a case report*

被引:10
作者
Subramanian, Susanth [1 ]
Jonathan, Gandham Edmond [1 ]
Patel, Bimal [2 ]
Prabhu, Krishna [1 ]
机构
[1] Christian Med Coll & Hosp, Dept Neurol Sci, Vellore, Tamil Nadu, India
[2] Christian Med Coll & Hosp, Dept Neuropathol, Vellore, Tamil Nadu, India
关键词
Primary synovial sarcoma; thoracic spine;
D O I
10.1080/02688697.2017.1418289
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: Synovial sarcoma is a rare mesenchymal malignant neoplasm that accounts for less than 10% of soft tissue sarcomas. About 95% of the sarcomas occur in the extremities. Primary synovial sarcomas of the spine are a rare tumor arising from the paravertebral regions, paraspinal muscles or epidural spaces. Purpose: To report an atypical radiological presentation of synovial sarcoma of the thoracic spine mimicking a nerve sheath tumor in an elderly adult and describe the management with review of the literature. Clinical presentation: A forty-six-year-old lady presented with clinical features of a thoracic intradural extramedullary cord compression at T7 level. She was Nurick grade 4 at presentation. MRI of the Thoracic spine with whole spine screening showed a contrast enhancing intradural extramedullary tumor at the T7-8 level; the tumor was exiting out through the left T7-8 neural foramina with foraminal widening. The possibility of a schwannoma was considered. Intervention: She underwent a T7-8 laminectomy and total excision of the tumor followed by posterior fusion. The biopsy was reported as synovial sarcoma. She subsequently underwent radiation and chemotherapy. She had marked improvement in her Neurological status and remained disease free at six months follow-up. Conclusion: Synovial sarcoma of the spine is a rare mesenchymal malignant neoplasm. One needs to consider Synovial sarcoma as one of the differential diagnosis of intradural tumors of the spine.
引用
收藏
页码:98 / 101
页数:4
相关论文
共 10 条
[1]   Metastatic Synovial Sarcoma With Cervical Spinal Cord Compression Treated With Posterior Ventral Resection: Case Report [J].
Arnold, Paul M. ;
Roh, Simon ;
Ha, Tung M. ;
Anderson, Karen K. .
JOURNAL OF SPINAL CORD MEDICINE, 2010, 33 (01) :80-84
[2]   Pediatric intradural extramedullary synovial sarcoma: Case report [J].
Greene, Stephanie ;
Hawkins, Douglas S. ;
Rutledge, Joe C. ;
Tsuchiya, Karen D. ;
Douglas, James ;
Ellenbogen, Richard G. ;
Avellino, Anthony M. .
NEUROSURGERY, 2006, 59 (06) :1339-1339
[3]  
Koehler Steven M, 2009, Spine J, V9, pe1, DOI 10.1016/j.spinee.2009.08.448
[4]   Imaging of synovial sarcoma with radiologic-pathologic correlation [J].
Murphey, Mark D. ;
Gibson, Michael S. ;
Jennings, Bryan T. ;
Crespo-Rodriguez, Ana M. ;
Fanburg-Smith, Julie ;
Gajewski, Donald A. .
RADIOGRAPHICS, 2006, 26 (05) :1543-1565
[5]   Synovial sarcoma of cervical intervertebral foramen: A rare cause of brachial weakness [J].
Naphade, Prashant S. ;
Desai, Meena S. ;
Shah, Rajan M. ;
Raut, Abhijit A. .
NEUROLOGY INDIA, 2011, 59 (05) :149-151
[6]  
Puffer Ross C, 2011, Surg Neurol Int, V2, P18, DOI 10.4103/2152-7806.76939
[7]   Diagnosis and management of synovial sarcoma [J].
Lor Randall R. ;
Schabel K.L.S. ;
Hitchcock Y. ;
Joyner D.E. ;
Albritton K.H. .
Current Treatment Options in Oncology, 2005, 6 (6) :449-459
[8]   SYNOVIAL SARCOMA OF THE THORACIC SPINE - A CASE-REPORT [J].
SIGNORINI, GC ;
PINNA, G ;
FRESCHINI, A ;
BONTEMPINI, L ;
ORE, GD .
SPINE, 1986, 11 (06) :629-631
[9]  
Sub SI, 2005, AM J NEURORADIOL, V26, P2402
[10]   TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies [J].
Terry, Jefferson ;
Saito, Tsuyoshi ;
Subramanian, Subbaya ;
Ruttan, Cindy ;
Antonescu, Cristina R. ;
Goldblum, John R. ;
Downs-Kelly, Erinn ;
Corless, Christopher L. ;
Rubin, Brian P. ;
van de Rijn, Matt ;
Ladanyi, Marc ;
Nielsen, Torsten O. .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2007, 31 (02) :240-246