Immune checkpoint inhibitor-related acral vasculitis

被引：34

作者：

Comont, Thibault ^{[1
]}

Sibaud, Vincent ^{[2
]}

Mourey, Loic ^{[3
]}

Cougoul, Pierre ^{[1
]}

Beyne-Rauzy, Odile ^{[1
]}

机构：

[1] CHU Toulouse, Purpan Inst Univ Canc Toulouse Oncopole, Serv Med Interne, 1 Av Joliot Curie, F-31100 Toulouse, France

[2] Inst Univ Canc Toulouse Oncopole, Serv Oncodermatol, Toulouse, France

[3] Inst Univ Canc Toulouse Oncopole, Serv Oncol Med, Toulouse, France

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2018年 / 6卷

关键词：

Immune check point inhibitors; Immune-related adverse events; Vasculitis;

D O I：

10.1186/s40425-018-0443-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Commentary on << Ipilimumab induced vasculitis >> by Padda A. et al., J Immunother Cancer. 2018;6:12. The authors diagnosed a small vessel vasculitis following treatment with anti-CTLA-4 (ipilimumab) for a resected stage III B/C melanoma. We report a similar case of acral vasculitis occurring with a combination of anti-CTLA-4 (tremelimumab) and anti-PD-L1 (durvalumab) prescribed for the management of a metastatic urothelial bladder cancer. In contrast to Padda A. et al., we observed a significant improvement with oral corticosteroids.

引用

页数：3

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