Synthesis, characterization and bio-activities of novel organotin(IV) complexes with N-phthaloyl-D-valine

被引：11

作者：

Ashfaq, M ^{[1
]}

Majeed, A

Baloch, MK

Khanzada, AWK

Shah, WU

机构：

[1] Gomal Univ, Dept Chem, Dera Ismail Khan, Pakistan

[2] Islamia Univ, Dept Chem, Bahawalpur, Pakistan

[3] Sindh Univ, NCE Analyt Chem, Jamshoro, Pakistan

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2003年 / 50卷 / 3A期

关键词：

N-phthaloyl-D-valine; triphenyltin chloride; tricyclohexyltin chloride; dibutyltin oxide;

D O I：

10.1002/jccs.200300054

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis and spectroscopic characterization of novel organotin(IV) complexes, are described. The monomeric compound possesses trans octahedral, and the dimeric complex is of six-coordinated skew trapezoidal bipyramidal geometry. The triorganotin(IV) complexes are assigned a polymeric trigonal bipyramidal and a tetrahedral structure. The ED50 test showed toxicity to brine shrimp naupli and bio-activities tests of the compounds exhibited antibacterial, antifungal and excellent anti-tumour activities.

引用

页码：361 / 368

页数：8

共 45 条

[1]

ASCHER KRS, 1979, PHYTOPARASITICA, V7, P17

[2] Organotin esters of N-phthaloylamino acids:: Synthesis, spectroscopic characterization, and biological activities [J].