A comprehensive list of bacterial pathogens infecting humans

被引：95

作者：

Bartlett, Abigail ^{[1
]}

Padfield, Daniel ^{[1
]}

Lear, Luke ^{[1
]}

Bendall, Richard

Vos, Michiel ^{[1
]}

机构：

[1] Univ Exeter, Med Sch, European Ctr Environm & Human Hlth, Environm & Sustainabil Inst, Penryn Campus, Exeter TR10 9FE, Devon, England

来源：

MICROBIOLOGY-SGM | 2022年 / 168卷 / 12期

关键词：

bacteria; human pathogens; species diversity; phylogenetic diversity; discovery; CLASSIFICATION CHANGES; PROPOSED NOMENCLATURE; MEDICAL IMPORTANCE; TAXONOMIC UPDATE;

D O I：

10.1099/mic.0.001269

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

There exists an enormous diversity of bacteria capable of human infection, but no up-to- date, publicly accessible list is available. Combining a pragmatic definition of pathogenicity with an extensive search strategy, we report 1513 bacterial pathogens known to infect humans described pre-2021. Of these, 73% were regarded as established (have infected at least three persons in three or more references) and 27% as putative (fewer than three known cases). Pathogen species belong to 10 phyla and 24 classes scattered throughout the bacterial phylogeny. We show that new human pathogens are discovered at a rapid rate. Finally, we discuss how our results could be expanded to a database, which could provide a useful resource for microbiologists. Our list is freely available and archived on GitHub and Zenodo and we have provided walkthroughs to facilitate access and use.

引用

页数：8

共 37 条

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