Convenient synthesis of drimenol and its oxidation with selenium dioxide

被引：11

作者：

Kuchkova, KI ^{[1
]}

Aricu, AN ^{[1
]}

Dragalin, IP ^{[1
]}

Vlad, PF ^{[1
]}

机构：

[1] Acad Stiinte Moldovei, Inst Chim, MD-2028 Kishinev, Moldova

来源：

RUSSIAN CHEMICAL BULLETIN | 2004年 / 53卷 / 12期

关键词：

terpenoids; drimenol; drimane-8; alpha; 11-diol; 11-monoacetate; drim-7-ene-9; drim-7-ene,11,12-diol; selenium dioxide; oxidation; dehydration;

D O I：

10.1007/s11172-005-0203-x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient synthesis of drimenol by treatment of readily available drimane-8 alpha,11-diol 11-monoacetate with sulfuric acid in ethanol under mild conditions was developed. Oxidation of drimenol with selenium dioxide gives known drim-7-ene-9 alpha,11-diol and drim-7-ene-11,12-diol as the major products.

引用

页码：2862 / 2865

页数：4

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