Path to Industrial Production of Calix[8 and 4]arenes

被引：2

作者：

Haase, Cornelius Heinz Werner ^{[1
]}

机构：

[1] SI Grp Inc, 2750 Balltown Rd, Schenectady, NY 12301 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 02期

关键词：

CALIXARENES;

D O I：

10.1021/acs.joc.9b02692

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective and high yield synthesis for the production of calix[8]arenes in concentrated reaction masses is described. Obtained purities are >98% and yields of >80%, with isolation by simple filtration. The developed approach allows for subsequent "in situ" formation of calix[4]arenes. The syntheses are amenable to large scale manufacturing. Kinetic observations during the formation of calix[4]arenes from calix[8]arenes are included. Furthermore, details related to "soluble" calix[4]arene are described.

引用

页码：603 / 611

页数：9

共 50 条

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