Butyrolactones from the Fermentation Products of the Endophytic Fungus Aspergillus versicolor

被引:16
作者
Zhou, Kun [1 ,2 ]
Zhu, Long [3 ]
Wang, Xinlin [3 ]
Zhang, Tiandong [3 ]
Wang, Yuede [1 ,2 ]
Dong, Wei [1 ,2 ]
Ji, Bingkun [1 ,2 ]
Yang, Haiying [1 ,2 ]
Du, Gang [1 ,2 ]
Hu, Qiufen [1 ,2 ]
Zhou, Min [1 ,2 ,3 ]
机构
[1] Yunnan Minzu Univ, State Ethn Affairs Commiss, Key Lab Chem Ethn Med Resources, Kunming 650031, Peoples R China
[2] Yunnan Minzu Univ, Minist Educ, Kunming 650031, Peoples R China
[3] China Tobacco Yunnan Ind Co Ltd, Ctr Technol, Kunming 650000, Peoples R China
基金
中国国家自然科学基金;
关键词
butyrolactones; Aspergillus versicolor; anti-tobacco mosaic virus activity; BUTENOLIDES;
D O I
10.1007/s10600-016-1719-z
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new butyrolactones, versicolactones E-F (1 and 2), along with three known butyrolactones (3-5), were isolated from the fermentation products of the endophytic fungus Aspergillus versicolor. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of 1-5 were evaluated. Compounds 1-5 showed modest anti-TMV activities with inhibition rates of 14.6-18.8%.
引用
收藏
页码:591 / 594
页数:4
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