Discovery of potent, non-peptide thrombin receptor antagonists.

被引：0
|
作者：
Chackalamannil, S
Xia, Y
Clasby, M
Greenlee, W
Doller, D
Eagen, K
Tsai, HS
Asberom, T
Lin, Y
Czarniecki, M
Ahn, HS
Foster, C
Boykow, G
机构：
[1] Schering Plough Res Inst, CNS Chem Res, CV, Kenilworth, NJ 07033 USA
[2] Schering Plough Res Inst, CNS Pharmacol, CV, Kenilworth, NJ 07033 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2001年 / 221卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
342-MEDI
引用
收藏
页码：U60 / U60
页数：1
相关论文
共 50 条
  • [1] Discovery and sar of the first non-peptide competitive human glucagon receptor antagonists.
    Madsen, P
    Knudsen, LB
    Wiberg, FC
    Carr, RD
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 216 : U259 - U259
  • [2] Non-peptide calcitonin gene-related peptide (CGRP) receptor antagonists.
    Daines, RA
    Sham, KKC
    Taggart, JJ
    Kingsbury, WD
    Chan, J
    Breen, A
    Disa, J
    Aiyar, N
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 237 - MEDI
  • [3] Discovery and, characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists
    McDonald, Iain M.
    Austin, Carol
    Buck, Ildiko M.
    Dunstone, David J.
    Gaffen, John
    Griffin, Eric
    Harper, Elaine A.
    Hull, Robert A. D.
    Kalindjian, S. Barret
    Linney, Ian D.
    Low, Caroline M. R.
    Patel, Dipa
    Pether, Michael J.
    Raynor, Michelle
    Roberts, Sonia P.
    Shaxted, Mark E.
    Spencer, John
    Steel, Katherine I. M.
    Sykes, David A.
    Wright, Paul T.
    Xun, Wei
    JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (20) : 4789 - 4792
  • [4] Discovery of potent, selective, non-steroidal mineralocorticoid receptor antagonists.
    Neel, DA
    Brown, ML
    Lander, PA
    Grese, TA
    Defauw, JM
    Doti, RA
    Fields, T
    Smith, S
    Wiest, SA
    Zimmerman, KM
    Steinberg, MI
    Jadhav, PK
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U46 - U46
  • [5] Superimposition of potent non-peptide AT(1) receptor antagonists with angiotensin II
    Theodoropoulou, E
    Mavromoustakos, T
    Panagiotopoulos, D
    Matsoukas, JM
    Smith, J
    LETTERS IN PEPTIDE SCIENCE, 1996, 3 (04): : 209 - 216
  • [6] Design and synthesis of a new class of highly potent non-peptide bradykinin B2 receptor agonists and antagonists.
    Abe, Y
    Kayakiri, H
    Satoh, S
    Inoue, T
    Sawada, Y
    Mizutani, T
    Oku, T
    Tanaka, H
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 218 : U1018 - U1018
  • [7] Discovery of potent, orally efficacious imidazolidinone-containing non-peptide alpha-v beta-3 antagonists.
    Meissner, RS
    Perkins, JJ
    Zartman, AE
    Duong, LT
    Fernandez-Metzler, C
    Gentile, MA
    Meng, Y
    Hartman, GD
    Kimmel, DB
    Leu, CT
    Nagy, RM
    Pennypacker, BL
    Prueksaritanont, T
    Rodan, GA
    Rodan, S
    Duggan, ME
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U45 - U45
  • [8] Discovery of novel non-peptide CCR1 receptor antagonists
    Ng, HP
    May, K
    Bauman, JG
    Ghannam, A
    Islam, I
    Liang, M
    Horuk, R
    Hesselgesser, J
    Snider, RM
    Perez, HD
    Morrissey, MM
    JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (22) : 4680 - 4694
  • [9] Synthesis and SAR studies with a first in class series of non-peptide motilin receptor antagonists.
    Xiang, MA
    Ryhczynski, P
    Chen, RHK
    Beavers, MP
    Combs, DW
    Gunnet, JI
    Hageman, W
    Moore, JB
    Zhou, LB
    Urbanski, M
    Demarest, KT
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 228 : U912 - U912
  • [10] Discovery and optimization of potent orally active small molecular thrombin receptor(PAR-1) antagonists.
    Kawahara, T
    Suzuki, S
    Matsuura, F
    Clark, RSJ
    Kogushi, M
    Kobayashi, H
    Hishinuma, L
    Sato, N
    Terauchi, T
    Kajiwara, A
    Matsuoka, T
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U21 - U21
12345