Cloning and identification of exon-intron organization of the rat ATP-citrate lyase gene

被引：5

作者：

Moon, YA ^{[1
]}

Kim, KS ^{[1
]}

Park, SW ^{[1
]}

Kim, YS ^{[1
]}

机构：

[1] YONSEI UNIV,COLL MED,INST GENET SCI,DEPT BIOCHEM & MOLEC BIOL,SEODAEMUN KU,SEOUL 120752,SOUTH KOREA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1996年 / 1307卷 / 03期

关键词：

ATP-citrate lyase gene; cloning; exon-intron organization;

D O I：

10.1016/0167-4781(96)00067-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The rat ATP-citrate lyase gene was cloned and the complete exon-intron organization of the gene has been identified. The ATP-citrate lyase gene, spanning about 55 kb, is divided into 29 exons that range in size from 30 to 986 base pairs. The sequences bordering the splice site junctions universally follow the GT/AG rule. Reverse transcription-polymerase chain reaction showed two forms of ACL mRNA; the one containing complete exons and the other lacking exon 14 were found in the brain, kidney, mammary gland, lung and liver. Also, the restriction fragment length polymorphisms were observed at intron 10 and intron 11 regions.

引用

页码：280 / 284

页数：5

共 50 条

[31] ATP-CITRATE LYASE KINASE AND CYCLIC AMP-DEPENDENT PROTEIN-KINASE PHOSPHORYLATE DIFFERENT SITES ON ATP-CITRATE LYASE
RAMAKRISHNA, S
PUCCI, DL
BENJAMIN, WB
JOURNAL OF BIOLOGICAL CHEMISTRY, 1981, 256 (20) : 213 - 216
[32] REGULATION OF ATP-CITRATE LYASE AT TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL LEVELS IN RAT-LIVER
KIM, KS
PARK, SW
KIM, YS
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 189 (01) : 264 - 271
[33] REGULATION OF ATP-CITRATE LYASE IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES
SPENCE, JT
PITOT, HC
ZALITIS, G
JOURNAL OF BIOLOGICAL CHEMISTRY, 1979, 254 (23) : 2169 - 2173
[34] ATP-CITRATE LYASE KINASE AND CYCLIC AMP-INDEPENDENT PROTEIN-KINASE PHOSPHORYLATE DIFFERENT SITES ON ATP-CITRATE LYASE
RAMAKRISHNA, S
BENJAMIN, WB
FEDERATION PROCEEDINGS, 1981, 40 (06) : 1720 - 1720
[35] PURIFICATION AND SOME PROPERTIES OF ATP-CITRATE LYASE FROM RAT-BRAIN
SZUTOWICZ, A
SRERE, PA
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, 221 (01) : 168 - 174
[36] REDOX CONTROL OF CATALYSIS IN ATP-CITRATE LYASE FROM RAT-LIVER
WELLS, TNC
SAXTY, BA
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 204 (01): : 249 - 255
[37] Systematic identification and characterization of exon-intron circRNAs
Zhong, Yinchun
Yang, Yan
Wang, Xiaolin
Ren, Bingbing
Wang, Xueren
Shan, Ge
Chen, Liang
GENOME RESEARCH, 2024, 34 (03) : 376 - 393
[38] Exon-intron organization of the human 5-HT3A receptor gene
Brüss, M
Eucker, T
Göthert, M
Bönisch, H
NEUROPHARMACOLOGY, 2000, 39 (02) : 308 - 315
[39] Physiological characterization of ATP-citrate lyase in Aspergillus niger
Chen, Hong
He, Xihong
Geng, Hongran
Liu, Hao
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2014, 41 (04) : 721 - 731
[40] EXON-INTRON ORGANIZATION IN GENES OF EARTHWORM AND VERTEBRATE GLOBINS
JHIANG, SM
GAREY, JR
RIGGS, AF
SCIENCE, 1988, 240 (4850) : 334 - 336

← 1 2 3 4 5 →