Doubly robust estimation of attributable fractions

被引:24
作者
Sjolander, Arvid [1 ]
Vansteelandt, Stijn [2 ]
机构
[1] Karolinska Inst, Dept Med Epidemiol & Biostat, S-17177 Stockholm, Sweden
[2] Univ Ghent, Dept Appl Math & Comp Sci, B-9000 Ghent, Belgium
基金
瑞典研究理事会;
关键词
Attributable fraction; attributable risk; doubly robust estimation; excess fraction; inverse probability weighting; maximum likelihood; RISK;
D O I
10.1093/biostatistics/kxq049
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The attributable fraction (AF) is a widely used measure to assess the impact of an exposure on a disease. It is commonly estimated through maximum likelihood, which requires a regression model for the outcome. Recently, it was demonstrated that the AF can also be estimated through inverse probability weighting, which requires a model for the exposure. In this paper, we derive doubly robust estimators for the AF. These estimators require one model for the outcome and one model for the exposure and are consistent if either model is correct, not necessarily both. We consider both cohort/cross-sectional studies and case-control studies.
引用
收藏
页码:112 / 121
页数:10
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