Ferrocene-Based Planar Chiral Imidazopyridinium Salts for Catalysis

被引：93

作者：

Check, Christopher T. ^{[1
]}

Jang, Ki Po ^{[1
]}

Schwamb, C. Benjamin ^{[1
]}

Wong, Alexander S. ^{[1
]}

Wang, Michael H. ^{[1
]}

Scheidt, Karl A. ^{[1
]}

机构：

[1] Northwestern Univ, Ctr Mol Innovat & Drug Discovery, Dept Chem, Evanston, IL 60208 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 14期

基金：

美国国家科学基金会;

关键词：

asymmetric synthesis; N-heterocyclic carbenes; organocatalysis; transition-metal catalysis; N-HETEROCYCLIC CARBENES; ASYMMETRIC CATALYSIS; OLEFIN METATHESIS; ENANTIOSELECTIVE SYNTHESIS; COORDINATION CHEMISTRY; NUCLEOPHILIC CARBENES; HOMOGENEOUS CATALYSIS; ELECTRONIC-PROPERTIES; GAMMA-BUTYROLACTONES; CONJUGATE ADDITIONS;

D O I：

10.1002/anie.201410118

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Planar chirality remains an underutilized control element in asymmetric catalysis. Factors that have limited its broader application in catalysis include poor catalyst performance and difficulties associated with the economical production of enantiopure planar chiral compounds. The construction of planar chiral azolium salts that incorporate a sterically demanding iron sandwich complex is now reported. Applications of this new N-heterocyclic carbene as both an organocatalyst and a ligand for transition-metal catalysis demonstrate its unprecedented versatility and potential broad utility in asymmetric catalysis.

引用

页码：4264 / 4268

页数：5

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