Green Synthesis of Five- and Six-membered N-heterocycles by Ultrasonic Irradiation in Aqueous Media

被引：5

作者：

Nogueira, Thais Cristina Mendonca ^{[1
]}

de Souza, Marcus Vinicius Nora ^{[1
]}

机构：

[1] Fundacao Oswaldo Cruz, Inst Tecnol Farmacos Far Manguinhos, Rua Sizenando Nabuco 100, BR-21041250 Rio De Janeiro, RJ, Brazil

来源：

CURRENT GREEN CHEMISTRY | 2021年 / 8卷 / 02期

关键词：

N-heterocycles; green chemistry; anti-cancer; ultrasound; sonochemistry; organic synthesis; MCR; ONE-POT SYNTHESIS; MICROWAVE-ASSISTED SYNTHESIS; CATALYST-FREE SYNTHESIS; IV AMMONIUM-NITRATE; EFFICIENT SYNTHESIS; SOLVENT-FREE; MULTICOMPONENT SYNTHESIS; ORGANIC-SYNTHESIS; 3-COMPONENT SYNTHESIS; ROOM-TEMPERATURE;

D O I：

10.2174/2213346108666210423120316

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Five- and six-membered N-heterocyclic compounds play an important role in medicinal chemistry and the development of new drugs. There is a constant demand for the development of novel biologically potent compounds, and there is also an increasing pressure to develop alternative and more sustainable synthetic methodologies following the Green Chemistry principles. Thus, the present review aims to compile the latest progress in the use of ultrasound irradiation in water conditions to mediate the synthesis of five- and six-membered N-heterocyclic compounds in an environmentally benign manner.

引用

页码：99 / 126

页数：28

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