Resveratrol Oligomers from Vatica albiramis

被引：45

作者：

Abe, Naohito ^{[1
]}

Ito, Tetsuro ^{[1
]}

Ohguchi, Kenji ^{[2
]}

Nasu, Minori ^{[1
]}

Masuda, Yuichi ^{[1
]}

Oyama, Masayoshi ^{[1
]}

Nozawa, Yoshinori ^{[2
,3
]}

Ito, Masafumi ^{[2
]}

Iinuma, Munekazu ^{[1
]}

机构：

[1] Gifu Pharmaceut Univ, Lab Pharmacognosy, Gifu 5011196, Japan

[2] Gifu Int Inst Biotechnol, Gifu 5040838, Japan

[3] Tokai Gakuin Univ, Gifu 5048511, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 09期

关键词：

STEM BARK; THW DIPTEROCARPACEAE; STILBENE GLUCOSIDES; ABSOLUTE STRUCTURES; SHOREA-HEMSLEYANA; AMPELOPSIN-B; CAREX-PUMILA; C-GLUCOSIDES; OLIGOSTILBENES; HOPEAPHENOL;

D O I：

10.1021/np1002675

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Five new stilbenoids, vatalbinosides A-E (1-5), and 13 known compounds (6-18) were isolated from the stem of Vatica albiramis. The effects of these new compounds on interleukin-1 beta-induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined. Three resveratrol tetramers, (-)-hopeaphenol (6), vaticanol C (13), and stenophyllol C (14), were identified as strong inhibitors of MMP-1 production.

引用

页码：1499 / 1506

页数：8

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