Temperature-Sensitive Fluorescent Organic Nanoparticles with Aggregation-Induced Emission for Long-Term Cellular Tracing

被引：125
|
作者：
Wang, Zhen
Yong, Tu-Ying
Wan, Jiangshan
Li, Zi-He
Zhao, Hao
Zhao, Yanbing
Gan, Lu
Yang, Xiang-Liang
Xu, Hui-Bi
Zhang, Chun [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Wuhan 430074, Hubei, Peoples R China
来源：
ACS APPLIED MATERIALS & INTERFACES | 2015年 / 7卷 / 05期
基金：
中国国家自然科学基金;
关键词：
tetraphenylethene (TPE); poly(N-isoproylacryamide); (PNIPAM); fluorescent organic nanopartices; aggregation-induced emission (AIE); long-term celluar tracing; QUANTUM DOTS; TUNABLE EMISSION; IN-VIVO; NANOGELS; TRACKING; THERAPY; FABRICATION; MICELLES; DELIVERY; POLYMER;
D O I：
10.1021/am509161y
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Temperature-sensitive organic nanoparticles with AIE effect were assembled in water from tetraphenylethene-based poly(N-isopropylacrylamide) (TPE-PNIPAM), which was synthesized by ATRP using TPE derivative as initiator. The size and fluorescence of TPE-PNIPAM nanoparticles can be tuned by varying the temperature. These nanoparticles can be internalized readily by HeLa cells and can be used as long-term tracer in live cells to be retained for as long as seven passages.
引用
收藏
页码：3420 / 3425
页数：6
相关论文
共 50 条
  • [41] Preparation of aggregation-induced emission dots for long-term two-photon cell imaging
    Ye, Qiang
    Chen, Shuangshuang
    Zhu, Dandan
    Lu, Xuemin
    Lu, Qinghua
    JOURNAL OF MATERIALS CHEMISTRY B, 2015, 3 (15) : 3091 - 3097
  • [42] Aggregation-induced emission enhancement of gold nanoclusters in metal-organic frameworks for highly sensitive fluorescent detection of bilirubin
    Xia, Mengfan
    Sui, Yucun
    Guo, Ying
    Zhang, Yaodong
    ANALYST, 2021, 146 (03) : 904 - 910
  • [43] Fluorescent Glycopolymer Nanoparticles Based on Aggregation-Induced Emission Dyes: Preparation and Bioimaging Applications
    Wang, Ke
    Zhang, Xiaoyong
    Zhang, Xiqi
    Yang, Bin
    Li, Zhen
    Zhang, Qingsong
    Huang, Zengfang
    Wei, Yen
    MACROMOLECULAR CHEMISTRY AND PHYSICS, 2015, 216 (06) : 678 - 684
  • [44] Facile fabrication and biological imaging applications of salicylaldehyde based fluorescent organic nanoparticles with aggregation-induced emission and ESIPT feature
    Yang, Saijiao
    Liu, Meiying
    Mao, Liucheng
    Xu, Dazhuang
    Huang, Hongye
    Chen, Junyu
    Wen, Yuanqing
    Deng, Fengjie
    Zhang, Xiaoyong
    Wei, Yen
    JOURNAL OF MOLECULAR LIQUIDS, 2019, 292
  • [45] Solventless synthesis of a Schiff base that forms highly fluorescent organic nanoparticles exhibiting aggregation-induced emission in aqueous media
    Omer, Khalid M.
    Mohammad, Sewara J.
    Raheem, Shvan J.
    JOURNAL OF EXPERIMENTAL NANOSCIENCE, 2016, 11 (15) : 1184 - 1192
  • [46] Ultrafast fabrication of fluorescent organic nanoparticles with aggregation-induced emission feature through the microwave-assisted Biginelli reaction
    Dong, Jiande
    Liu, Meiying
    Jiang, Ruming
    Huang, Hongye
    Huang, Qiang
    Wen, Yuanqing
    Tian, Jianwen
    Dai, Yanfeng
    Zhang, Xiaoyong
    Wei, Yen
    DYES AND PIGMENTS, 2019, 165 : 90 - 96
  • [47] NANOPARTICLES WITH AGGREGATION-INDUCED EMISSION FOR MONITORING LONG TIME CELL MEMBRANE INTERACTIONS
    Cheng, Hao
    Qin, Wei
    Zhu, Zhenfeng
    Qian, Jun
    Qin, Anjun
    Tang, Ben Zhong
    He, Sailing
    PROGRESS IN ELECTROMAGNETICS RESEARCH-PIER, 2013, 140 : 313 - 325
  • [48] Aggregation-Induced Emission Fluorogens-Doped Silica Nanoparticles Using for Cellular Imaging
    Lai, Chin-Wei
    Chang, Cheng-Chung
    2019 13TH IEEE INTERNATIONAL CONFERENCE ON NANO/MOLECULAR MEDICINE & ENGINEERING (IEEE-NANOMED 2019), 2019, : 95 - 95
  • [49] A sensitive fluorescent probe for alkaline phosphatase and an activity assay based on the aggregation-induced emission effect
    Zhang, Wenjuan
    Yang, Hanxiao
    Li, Nan
    Zhao, Na
    RSC ADVANCES, 2018, 8 (27): : 14995 - 15000
  • [50] Selective and sensitive fluorescent enhancement detection of keratin in aqueous media with aggregation-induced emission characteristics
    Sun, Jiaojiao
    Cao, Jian
    Wang, Jinjie
    Wang, Jincheng
    Wang, Shuxin
    SENSORS AND ACTUATORS B-CHEMICAL, 2019, 293 (159-165) : 159 - 165
12345