Co-ligation of the B cell receptor with complement receptor 2 (CR2/CD21) using its natural ligand C3dg: Activation without engagement of an inhibitory signaling pathway

被引:0
|
作者
Lyubchenko, T
Dal Porto, J
Cambier, J
Holers, M
机构
[1] Univ Colorado, Hlth Sci Ctr, Dept Med, Denver, CO 80262 USA
[2] Natl Jewish Med Res Ctr, Dept Immunol, Denver, CO 80206 USA
来源
FASEB JOURNAL | 2005年 / 19卷 / 04期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A951 / A951
页数:1
相关论文
共 50 条
  • [31] CHARACTERIZATION OF A COMPLEMENT RECEPTOR-2 (CR2, CD21) LIGAND-BINDING SITE FOR C3 - AN INITIAL MODEL OF LIGAND INTERACTION WITH 2 LINKED SHORT CONSENSUS REPEAT MODULES
    MOLINA, H
    PERKINS, SJ
    GUTHRIDGE, J
    GORKA, J
    KINOSHITA, T
    HOLERS, VM
    JOURNAL OF IMMUNOLOGY, 1995, 154 (10): : 5426 - 5435
  • [32] Human complement receptor (CR2/CD21) is a receptor for DNA: implications for its roles in the immune response and the pathogenesis of systemic lupus erythematosus (SLE)
    Asokan, R
    Lyubchenko, T
    Szakonyi, G
    Hannan, JP
    Kotzin, BL
    Chen, XS
    Holers, VM
    MOLECULAR IMMUNOLOGY, 2004, 41 (2-3) : 205 - 205
  • [33] Changes in chromatin accessibility across the complement receptor 2 (CR2/CD21) gene promoter occurs during different stages of B cell development
    Cruikshank, Mark N.
    Fenwick, Emily J.
    Abraham, Lawrence J.
    Ulgiati, Daniela
    MOLECULAR IMMUNOLOGY, 2007, 44 (1-3) : 162 - 162
  • [34] Human complement receptor (CR2/CD21) is a receptor for DNA: Implications for its roles in the immune response and the pathogenesis of systemic lupus erythematosus (SLE)
    Asokan, R
    Lyubchenko, T
    Szakonyi, G
    Aramowizc, K
    Boackle, S
    Chen, XJ
    Holers, VM
    FASEB JOURNAL, 2005, 19 (04): : A886 - A886
  • [35] Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220
    Sarrias, MR
    Franchini, S
    Canziani, G
    Argyropoulos, E
    Moore, WT
    Sahu, A
    Lambris, JD
    JOURNAL OF IMMUNOLOGY, 2001, 167 (03): : 1490 - 1499
  • [36] Complement receptor CR2/CD21 proximal promoter activity is critically dependent upon a cell type specific repressor.
    Ulgiati, D
    Holers, VM
    ARTHRITIS AND RHEUMATISM, 2001, 44 (09): : S203 - S203
  • [37] An intronic silencer regulates B lymphocyte cell- and stage-specific expression of the human complement receptor type 2 (CR2, CD21) gene
    Makar, KW
    Pham, CTN
    Dehoff, MH
    O'Connor, SM
    Jacobi, SM
    Holers, VM
    JOURNAL OF IMMUNOLOGY, 1998, 160 (03): : 1268 - 1278
  • [38] Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21)
    Pappworth, Isabel Y.
    Kulik, Liudmila
    Haluszczak, Catherine
    Reuter, Jason W.
    Holers, V. Michael
    Marchbank, Kevin J.
    MOLECULAR IMMUNOLOGY, 2009, 46 (06) : 1042 - 1049
  • [39] Epitope mapping using the X-ray crystallographic structure of complement receptor type 2 (CR2)/CD21: Identification of a highly inhibitory monoclonal antibody that directly recognizes the CR2-C3d interface
    Guthridge, JM
    Young, K
    Gipson, MG
    Sarrias, MR
    Szakonyi, G
    Chen, XJS
    Malaspina, A
    Donoghue, E
    James, JA
    Lambris, JD
    Moir, SA
    Perkins, SJ
    Holers, VM
    JOURNAL OF IMMUNOLOGY, 2001, 167 (10): : 5758 - 5766
  • [40] COMPLEMENT RECEPTOR TYPE-2 (CD21) ENHANCES MIGM-INDUCED B-CELL ACTIVATION
    CARTER, RH
    NG, YC
    FEARON, DT
    FASEB JOURNAL, 1988, 2 (04): : A872 - A872