To assess the therapy relative to indication, effectiveness, safety and adherence in patients with Alzheimer's disease (AD). An interventional, prospective, non-randomized study was conducted in a single secondary care center in Brazil. The pharmacist-led Medication Therapy Management (MTM) was conducted to detect drug-related problems (DRPs) at baseline and after six months of intervention. The health status outcomes (i.e. cognitive screening tests; levels of glucose; total cholesterol; triglycerides; thyroid stimulating hormone; serum free thyroxine; and blood pressure) were measured. 66 patients with AD were included, of whom 55 patients completed the follow-up of six months. 36 patients (36/55) were non-adherent to AD drug therapy. Out of detected 166 DRPs, 116 were solved. Four patients were withdrawn from the AD protocol due to resolution of prodromal symptoms. On the conclusion of the study, the MTM improved and controlled blood pressure, glucose, total cholesterol and triglycerides levels (p<0.05). The pharmacist-led MTM was effective in solving 69.8% of DRPs, improving and controlling the clinical parameters evaluated.
机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Xing Peng
Peiqi Xing
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Peiqi Xing
Xiuhui Li
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Xiuhui Li
Ying Qian
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Ying Qian
Fuhai Song
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Fuhai Song
Zhouxian Bai
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Zhouxian Bai
Guangchun Han
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of SciencesCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Guangchun Han
Hongxing Lei
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机构:
CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
Cunji Medical School,University of Chinese Academy of Sciences
Center of Alzheimer’s Disease,Beijing Institute for Brain DisordersCAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences
机构:
Queens Univ Belfast, Sch Med, Univ Rd, Belfast BT7 1NN, Antrim, North IrelandInt Med Univ, Sch Hlth Sci, Div Biomed Sci & Biotechnol, 126,Jalan Jalil Perkasa 19, Kuala Lumpur 57000, Malaysia
Ko, Yi
Chye, Soi Moi
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Int Med Univ, Sch Hlth Sci, Div Biomed Sci & Biotechnol, 126,Jalan Jalil Perkasa 19, Kuala Lumpur 57000, MalaysiaInt Med Univ, Sch Hlth Sci, Div Biomed Sci & Biotechnol, 126,Jalan Jalil Perkasa 19, Kuala Lumpur 57000, Malaysia
机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Peng, Xing
Xing, Peiqi
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机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Xing, Peiqi
Li, Xiuhui
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h-index: 0
机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Li, Xiuhui
Qian, Ying
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h-index: 0
机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Qian, Ying
Song, Fuhai
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机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Song, Fuhai
Bai, Zhouxian
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机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Bai, Zhouxian
Han, Guangchun
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h-index: 0
机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Han, Guangchun
Lei, Hongxing
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h-index: 0
机构:
Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Cunji Med Sch, Beijing 100049, Peoples R China
Beijing Inst Brain Disorders, Ctr Alzheimers Dis, Beijing 100053, Peoples R ChinaChinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing 100101, Peoples R China
机构:
North Sichuan Med Coll, Sch Sports Med & Rehabil, Nanchong 637000, Sichuan, Peoples R ChinaNorth Sichuan Med Coll, Sch Sports Med & Rehabil, Nanchong 637000, Sichuan, Peoples R China
Zeng, Zhengzhong
Zhang, Hu
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机构:
Wuhan Sports Univ, Coll Sports Med, Wuhan 430079, Peoples R ChinaNorth Sichuan Med Coll, Sch Sports Med & Rehabil, Nanchong 637000, Sichuan, Peoples R China
Zhang, Hu
Wang, Xianping
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机构:
Taizhou Univ, Sch Med, Taizhou 318000, Zhejiang, Peoples R ChinaNorth Sichuan Med Coll, Sch Sports Med & Rehabil, Nanchong 637000, Sichuan, Peoples R China
Wang, Xianping
Shen, Jiawen
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机构:
Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Rehabil Med Ctr, Linhai 317000, Zhejiang, Peoples R ChinaNorth Sichuan Med Coll, Sch Sports Med & Rehabil, Nanchong 637000, Sichuan, Peoples R China
Shen, Jiawen
Chen, Danyang
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机构:
Wenzhou Med Univ, Taizhou Hosp Zhejiang Prov, Rehabil Med Ctr, Linhai 317000, Zhejiang, Peoples R ChinaNorth Sichuan Med Coll, Sch Sports Med & Rehabil, Nanchong 637000, Sichuan, Peoples R China