Three-component synthesis of 1,4-benzothiazines via iodide-catalyzed aerobic C-H sulfuration with elemental sulfur

被引：17

作者：

Jiang, Jingjing ^{[1
]}

Tuo, Xiaotong ^{[1
]}

Fu, Zhuquan ^{[1
]}

Huang, Huawen ^{[1
]}

Deng, Guo-Jun ^{[1
]}

机构：

[1] Xiangtan Univ, Coll Chem, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environm Friendly Chem & Applicat,Minist, Xiangtan 411105, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2020年 / 18卷 / 17期

基金：

中国国家自然科学基金;

关键词：

CONTROLLED SELECTIVE SYNTHESIS; TRISULFUR RADICAL-ANION; S BOND FORMATION; MOLECULAR-OXYGEN; FACILE SYNTHESIS; DERIVATIVES; THIAZOLES; FUNCTIONALIZATION; OXIDATION; INDOLES;

D O I：

10.1039/d0ob00074d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, iodide-catalyzed aerobic synthesis of 1,4-benzothiazines via functionalization of multiple C-H bonds with elemental sulfur is described. Beyond the well-established thiazole formation from elemental sulfur, this method provides the first access to the corresponding six-membered N,S-heterocyclic products via direct functionalization of multiple C-H bonds. Hence, 1,4-benzothiazine products were generated in satisfactory yields with a range of compatible functionalities.

引用

页码：3234 / 3238

页数：5

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