A Model for Magnetic Nanoparticles Transport in a Channel for Targeted Drug Delivery

Magnetic Targeted Drug Delivery System (MTDDS), based upon magnetic particles under the action of an external magnetic field, is an effective technique for drug therapy. The aim of the drug targeting is to decrease the amount of drug delivered to healthy tissue, while maintaining the therapeutic action at the desired site. In this work, a mathematical model is presented for predicting magnetic nanoparticles transport in a channel for targeted drug delivery. The fluid flow composed of magnetic nanoparticles in a uniform channel is studied under the influence of magnetic field. The governing nonlinear partial differential equations for both the fluid and nanoparticles are solved using finite difference scheme and simulations are performed on MATLAB. Results show the decrease in velocity of fluid as well as magnetic nanoparticles by increasing the magnetic field. (C) 2015 The Authors. Published by Elsevier Ltd.