Synthesis of new tri- and tetraheterocyclic systems: 1,3-dipolar cycloaddition of nitrilimines on 2,7-dimethyl-4-phenyl-3H-1,5-benzodiazepin

被引：130

作者：

Essaber, M

Baouid, A

Hasnaoui, A ^{[1
]}

Benharref, A

Lavergne, JP

机构：

[1] Univ Cadi Ayyad, Fac Sci Semlalia, Dept Chim, CNCPRST,Lab Chim Subst Nat & Heterocycles, Marrakech, Morocco

[2] USTL, Lab Aminoacides & Peptides, F-34095 Montpellier 5, France

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 22期

关键词：

D O I：

10.1080/00397919809458689

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report here a one-step synthesis of a new series of tri and tetraheterocyclic systems by the mixed condensation reactions of N-aryl-C-ethoxycarbonylnitrilimines and diarylnitrilimines with 2,7-dimethyl-4-phenyl-3H-1,5-benzodiazepine. This 1,3-dipolar cycloaddition is completely peri and regioselective. The structure of these products has been confirmed by H-1, C-13 NMR, mass spectroscopic and X-ray crystallographic analysis.

引用

页码：4097 / 4104

页数：8

共 14 条

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AVERSA MC, 1989, J HETEROCYCLIC CHEM, V26, P1619

[2]

Baouid A, 1996, B SOC CHIM BELG, V105, P339

[3]

BAOUID A, 1994, B SOC CHIM BELG, V103, P743

[4] 7-MEMBERED HETEROCYCLIC COMPOUNDS .1. 1,5-BENZODIAZEPINES AND DERIVATIVES OF 3,6-DIAZA-4,5-BENZOTROPONE [J].