An investigation on the biological activity of Combretum species

被引:111
作者
McGaw, LJ
Rabe, T
Sparg, SG
Jäger, AK
Eloff, JN
van Staden, J
机构
[1] Univ Natl Pietermaritzburg, Sch Bot & Zool, Res Ctr Plant Growth & Dev, ZA-3209 Scottsville, South Africa
[2] Univ Pretoria, Dept Pharmacol, ZA-0001 Pretoria, South Africa
基金
新加坡国家研究基金会;
关键词
anti-bilharzia; anti-cancer; anti-inflammatory; anthelmintic; combretum; traditional medicine;
D O I
10.1016/S0378-8741(00)00405-0
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Leaf extracts of 20 Combretum species, many of which are used in southern African traditional medicine, were screened for anti-inflammatory, anthelmintic, anti-bilharzia (antischistosomal) and DNA-damaging activity. Significant activity in more than one bioassay was exhibited by Combretum apiculatum, Combretum hereroense, Combretum molle and Combretum mossambicense. Ethyl acetate extracts were generally most active, followed by acetone and then water extracts. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
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页码:45 / 50
页数:6
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