Chromosome Organizaton in Simple and Complex Unicellular Organisms

被引：0
作者：
O'Sullivan, Justin M. [1 ]
机构：
[1] Massey Univ, Inst Nat Sci, Auckland, New Zealand
来源：
CURRENT ISSUES IN MOLECULAR BIOLOGY | 2011年 / 13卷 / 02期
关键词：
ESCHERICHIA-COLI CHROMOSOME; RIBOSOMAL-RNA OPERONS; MACRODOMAIN ORGANIZATION; ACTIVE TRANSCRIPTION; YEAST; DNA; PROTEIN; SEGREGATION; CHROMATIN; LOCALIZATION;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The genomes of unicellular organisms form complex 3-dimensional structures. This spatial organization is hypothesized to have a significant role in genomic function. Spatial organization is not limited solely to the three-dimensional folding of the chromosome(s) in genomes but also includes genome positioning, and the folding and compartmentalization of any additional genetic material (e.g. episomes) present within complex genomes. In this comment, I will highlight similarities in the spatial organization of eukaryotic and prokaryotic unicellular genomes.
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共 78 条
[1]  
[Anonymous], INTEGRATIVE BIOPHYSI
[2]  
[Anonymous], J CELL SCI IN PRESS
[3]  
[Anonymous], CURRENT OPINION CELL
[4]   Structural basis for cooperative DNA binding by CAP and lac repressor [J].
Balaeff, A ;
Mahadevan, L ;
Schulten, K .
STRUCTURE, 2004, 12 (01) :123-132
[5]   Defining a centromere-like element in Bacillus subtilis by identifying the binding sites for the chromosome-anchoring protein RacA [J].
Ben-Yehuda, S ;
Fujita, M ;
Liu, XS ;
Gorbatyuk, B ;
Skoko, D ;
Yan, J ;
Marko, JF ;
Liu, JS ;
Eichenberger, P ;
Rudner, DZ ;
Losick, R .
MOLECULAR CELL, 2005, 17 (06) :773-782
[6]   RacA, a bacterial protein that anchors chromosomes to the cell poles [J].
Ben-Yehuda, S ;
Rudner, DZ ;
Losick, R .
SCIENCE, 2003, 299 (5606) :532-536
[7]   High-resolution statistical mapping reveals gene territories in live yeast [J].
Berger, Axel B. ;
Cabal, Ghislain G. ;
Fabre, Emmanuelle ;
Duong, Tarn ;
Buc, Henri ;
Nehrbass, Ulf ;
Olivo-Marin, Jean-Christophe ;
Gadal, Olivier ;
Zimmer, Christophe .
NATURE METHODS, 2008, 5 (12) :1031-1037
[8]   Homologous gene sequences mediate transcription-domain formation [J].
Binnie, Alexandra ;
Castelo-Branco, Pedro ;
Monks, Joan ;
Proudfoot, Nicholas J. .
JOURNAL OF CELL SCIENCE, 2006, 119 (18) :3876-3887
[9]   Spatial arrangement and macrodomain organization of bacterial chromosomes [J].
Boccard, F ;
Esnault, E ;
Valens, M .
MOLECULAR MICROBIOLOGY, 2005, 57 (01) :9-16
[10]   Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes [J].
Bolzer, A ;
Kreth, G ;
Solovei, I ;
Koehler, D ;
Saracoglu, K ;
Fauth, C ;
Müller, S ;
Eils, R ;
Cremer, C ;
Speicher, MR ;
Cremer, T .
PLOS BIOLOGY, 2005, 3 (05) :826-842
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