Performance of the T2Candida Panel for the Diagnosis of Intra-abdominal Candidiasis

被引：28

作者：

Lamoth, Frederic ^{[1
,2
,3
]}

Clancy, Cornelius J. ^{[4
]}

Tissot, Frederic ^{[1
,2
]}

Squires, Kevin ^{[4
]}

Eggimann, Philippe ^{[2
,5
]}

Flueckiger, Ursula ^{[6
,7
]}

Siegemund, Martin ^{[8
]}

Orasch, Christina ^{[9
]}

Zimmerli, Stefan ^{[10
]}

Calandra, Thierry ^{[1
,2
]}

Marchetti, Oscar ^{[1
,2
,11
]}

Nguyen, Minh H. ^{[4
]}

Bochud, Pierre-Yves ^{[1
,2
]}

机构：

[1] Lausanne Univ Hosp, Dept Med, Infect Dis Serv, Lausanne, Switzerland

[2] Univ Lausanne, Lausanne, Switzerland

[3] Lausanne Univ Hosp, Dept Labs, Inst Microbiol, Lausanne, Switzerland

[4] Univ Pittsburgh, Med Ctr, Div Infect Dis, Pittsburgh, PA USA

[5] Lausanne Univ Hosp, Serv Orthoped & Traumatol, Lausanne, Switzerland

[6] Univ Hosp Basel, Div Infect Dis, Basel, Switzerland

[7] Univ Hosp Basel, Hosp Epidemiol, Dept Med, Basel, Switzerland

[8] Univ Hosp Basel, Intens Care Unit, Basel, Switzerland

[9] Hirslanden Klin St Anna, Luzern, Switzerland

[10] Bern Univ Hosp, Dept Infect Dis, Bern, Switzerland

[11] Ensemble Hosp Cote, Hop Morges, Morges, Switzerland

来源：

OPEN FORUM INFECTIOUS DISEASES | 2020年 / 7卷 / 03期

关键词：

invasive candidiasis; candidemia; T2 magnetic resonance; blood cultures; beta-glucan; INVASIVE CANDIDIASIS; BLOOD; OUTCOMES; GLUCAN;

D O I：

10.1093/ofid/ofaa075

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Performance of T2Candida for detecting intra-abdominal candidiasis (IAC) was assessed in 48 high-risk patients. T2Candida sensitivity/specificity and positive/negative predictive values were 33%/93% and 71%/74%, respectively. IAC was present in 100% of cases with concordant positive T2Candida/1,3-beta-d-glucan and absent in 90% of concordant negative results. Combination T2Candida/1,3-beta-d-glucan may help guide treatment decisions.

引用

页数：3

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