共 82 条
Heart Failure and Thermoregulatory Control: Can Patients With Heart Failure Handle the Heat?
被引:23
作者:
Balmain, Bryce N.
[1
,2
]
Sabapathy, Surendn
[1
,2
]
Jay, Ollie
[3
,4
]
Adsett, Julie
[5
]
Stewart, Glenn M.
[1
,2
,6
]
Jayasinghe, Rohan
[1
,7
]
Morris, Norman R.
[1
,2
]
机构:
[1] Menzies Hlth Inst Queensland, Gold Coast, Qld, Australia
[2] Griffith Univ, Sch Allied Hlth Sci, Gold Coast Campus, Gold Coast, Qld 4222, Australia
[3] Univ Sydney, Fac Hlth Sci, Thermal Ergon Lab, Exercise & Sport Sci, Sydney, NSW, Australia
[4] Univ Sydney, Charles Perkins Ctr, Sydney, NSW, Australia
[5] Royal Brisbane & Womens Hosp, Heart Failure Serv, Brisbane, Qld, Australia
[6] Mayo Clin, Div Cardiovasc Dis, Rochester, MN USA
[7] Gold Coast Univ Hosp, Cardiol, Gold Coast, Qld, Australia
关键词:
Cardiovascular;
thermoregulation;
heat;
SKIN BLOOD-FLOW;
ENDOTHELIAL FUNCTION;
SYMPATHETIC ACTIVATION;
PROLONGED EXERCISE;
DIASTOLIC FUNCTION;
BODY-TEMPERATURE;
WAON THERAPY;
RESPONSES;
MECHANISMS;
TETRAHYDROBIOPTERIN;
D O I:
10.1016/j.cardfail.2017.04.003
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Upon heat exposure, the thermoregulatory system evokes reflex increases in sweating and skin blood flow responses to facilitate heat dissipation and maintain heat balance to prevent the continuing rise in core temperature. These heat dissipating responses are mediated primarily by autonomic and cardiovascular adjustments; which, if attenuated, may compromise thermoregulatory control. In patients with heart failure (HF), the neurohumoral and cardiovascular dysfunction that underpins this condition may potentially impair thermoregulatory responses and, consequently, place these patients at a greater risk of heat-related illness. The aim of this review is to describe thermoregulatory mechanism and the factors that may increase the risk of heat-related illness in patients with HF. An understanding of the mechanisms responsible for impaired thermoregulatory control in HF patients is of particular importance, given the current and projected increase in frequency and intensity of heat waves, as well as the promotion of regular exercise as a therapeutic modality. Furthermore, novel therapeutic strategies that may improve thermoregulatory control in HF, and the clinical relevance of this work in this population will be discussed.
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页码:621 / 627
页数:7
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