Chemical constituents of Osyris alba and their antiparasitic activities

被引：14

作者：

Al-Jaber, Hala I. ^{[2
]}

Mosleh, Ibrahim M. ^{[1
]}

Mallouh, Abdallah ^{[3
]}

Abu Salim, Omar M. ^{[3
]}

Abu Zarga, Musa H. ^{[2
]}

机构：

[1] Univ Jordan, Fac Sci, Dept Biol Sci, Amman, Jordan

[2] Univ Jordan, Fac Sci, Dept Chem, Amman, Jordan

[3] Al Kuds Med Labs, Zarka, Jordan

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2010年 / 12卷 / 09期

关键词：

osyrisine; Osyris alba; pyrrolizidine alkaloids; catechin; catechin-3-O--l-rhamnopyranoside; antiparasitic activity; METRONIDAZOLE; PYRROLIZIDINE; GIARDIA; L;

D O I：

10.1080/10286020.2010.502892

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical investigation of Osyris alba L. (Santalaceae) of Jordanian origin resulted in the isolation and identification of one new pyrrolizidine alkaloid, osyrisine (1), together with 16 other known compounds. The structures of all compounds were established on the basis of spectroscopic analysis. Osyrisine, catechin, and catechin-3-O--l-rhamnopyranoside exhibited a significant level of antiparasitic activity against two parasites, Entamoeba histolytica and Giardia intestinalis.

引用

页码：814 / 820

页数：7

共 20 条

[1]

Agrawal P.K., 1989, CARBON 13 NMR FLAVON

[2] KILLING OF GIARDIA-LAMBLIA BY CRYPTDINS AND CATIONIC NEUTROPHIL PEPTIDES [J].