An efficient method for opening nonactivated aziridines with TMS azide: application in the synthesis of chiral 1,2-diaminocyclohexane

被引：59

作者：

Chandrasekhar, M ^{[1
]}

Sekar, G ^{[1
]}

Singh, VK ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)01793-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of N-substituted aziridines have been opened with TMS azide in MeCN at rt in the absence of any Lewis acid. The reaction was extended to the synthesis of (R,R)- and (S,S)-1,2-diaminocyclohexane. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：10079 / 10083

页数：5

共 16 条

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