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Using fluorous amino acids to modulate the biological activity of an antimicrobial peptide
被引:83
作者
:
Gottler, Lindsey M.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Gottler, Lindsey M.
[
1
]
Lee, Hyang-Yeol
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Lee, Hyang-Yeol
[
1
]
Shelburne, Charles E.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Sch Dent, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Shelburne, Charles E.
[
2
]
Ramamoorthy, Ayyalusamy
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Ramamoorthy, Ayyalusamy
[
1
]
Marsh, E. Neil G.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Marsh, E. Neil G.
[
1
]
机构
:
[1]
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
[2]
Univ Michigan, Sch Dent, Ann Arbor, MI 48109 USA
来源
:
CHEMBIOCHEM
|
2008年
/ 9卷
/ 03期
关键词
:
antimicrobial agents;
fluorine;
isothermal titration calorimetry;
membrane permeabilization;
peptides;
D O I
:
10.1002/cbic.200700643
中图分类号
:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号
:
071010 ;
081704 ;
摘要
:
[No abstract available]
引用
收藏
页码:370 / 373
页数:4
相关论文
共 33 条
[1]
A short and efficient synthesis of L-5,5,5,5',5',5'-hexafluoroleucine from N-Cbz-L-serine
[J].
Anderson, JT
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Anderson, JT
;
Toogood, PL
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Toogood, PL
;
Marsh, ENG
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Marsh, ENG
.
ORGANIC LETTERS,
2002,
4
(24)
:4281
-4283
[2]
De novo design of defined helical bundles in membrane environments
[J].
Bilgiçer, B
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Bilgiçer, B
;
Kumar, K
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Kumar, K
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2004,
101
(43)
:15324
-15329
[3]
A coiled coil with a fluorous core
[J].
Bilgiçer, B
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Bilgiçer, B
;
Fichera, A
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Fichera, A
;
Kumar, K
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Kumar, K
.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,
2001,
123
(19)
:4393
-4399
[4]
BOMAN HG, 1995, ANNU REV IMMUNOL, V13, P61, DOI 10.1146/annurev.iy.13.040195.000425
[5]
Helix propensity of highly fluorinated amino acids
[J].
Chiu, Hsien-Po
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Chiu, Hsien-Po
;
Suzuki, Yuta
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Suzuki, Yuta
;
Gullickson, Donald
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Gullickson, Donald
;
Ahmad, Raheel
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0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Ahmad, Raheel
;
Kokona, Bashkim
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引用数:
0
h-index:
0
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SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Kokona, Bashkim
;
Fairman, Robert
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0
引用数:
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h-index:
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SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Fairman, Robert
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Cheng, Richard P.
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0
h-index:
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SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Cheng, Richard P.
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,
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128
(49)
:15556
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[6]
Anticancer α-helical peptides and structure/function relationships underpinning their interactions with tumour cell membranes
[J].
Dennison, Sarah R.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Dennison, Sarah R.
;
Whittaker, Michelle
论文数:
0
引用数:
0
h-index:
0
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Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Whittaker, Michelle
;
Harris, Frederick
论文数:
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0
h-index:
0
机构:
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Harris, Frederick
;
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0
引用数:
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h-index:
0
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Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Phoenix, David A.
.
CURRENT PROTEIN & PEPTIDE SCIENCE,
2006,
7
(06)
:487
-499
[7]
The introduction of fluorine atoms or trifluoromethyl groups in short cationic peptides enhances their antimicrobial activity
[J].
Gimenez, Diana
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Gimenez, Diana
;
Andreu, Cecilia
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0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Andreu, Cecilia
;
del Olmo, Marcel-li
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
del Olmo, Marcel-li
;
Varea, Teresa
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0
引用数:
0
h-index:
0
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Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Varea, Teresa
;
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h-index:
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Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Diaz, Dolores
;
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Asensio, Gregorio
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[8]
MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain
[J].
Hallock, KJ
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h-index:
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Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Ramamoorthy, A
.
BIOPHYSICAL JOURNAL,
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(05)
:3052
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[9]
Cytotoxic and allergenic potential of bioactive proteins and peptides
[J].
Hartmann, Rainer
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h-index:
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Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Hartmann, Rainer
;
Wal, Jean-Michel
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h-index:
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机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Wal, Jean-Michel
;
Bernard, Herve
论文数:
0
引用数:
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h-index:
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机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Bernard, Herve
;
Pentzien, Anne-Kathrin
论文数:
0
引用数:
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h-index:
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机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Pentzien, Anne-Kathrin
.
CURRENT PHARMACEUTICAL DESIGN,
2007,
13
(09)
:897
-920
[10]
Modulating protein structure with fluorous amino acids: Increased stability and native-like structure conferred on a 4-helix bundle protein by hexafluoroleucine
[J].
Lee, HY
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Lee, HY
;
Lee, KH
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Lee, KH
;
Al-Hashimi, HM
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Al-Hashimi, HM
;
Marsh, ENG
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Marsh, ENG
.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,
2006,
128
(01)
:337
-343
←
1
2
3
4
→
共 33 条
[1]
A short and efficient synthesis of L-5,5,5,5',5',5'-hexafluoroleucine from N-Cbz-L-serine
[J].
Anderson, JT
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Anderson, JT
;
Toogood, PL
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Toogood, PL
;
Marsh, ENG
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Marsh, ENG
.
ORGANIC LETTERS,
2002,
4
(24)
:4281
-4283
[2]
De novo design of defined helical bundles in membrane environments
[J].
Bilgiçer, B
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Bilgiçer, B
;
Kumar, K
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Kumar, K
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2004,
101
(43)
:15324
-15329
[3]
A coiled coil with a fluorous core
[J].
Bilgiçer, B
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Bilgiçer, B
;
Fichera, A
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Fichera, A
;
Kumar, K
论文数:
0
引用数:
0
h-index:
0
机构:
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Tufts Univ, Dept Chem, Medford, MA 02155 USA
Kumar, K
.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,
2001,
123
(19)
:4393
-4399
[4]
BOMAN HG, 1995, ANNU REV IMMUNOL, V13, P61, DOI 10.1146/annurev.iy.13.040195.000425
[5]
Helix propensity of highly fluorinated amino acids
[J].
Chiu, Hsien-Po
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Chiu, Hsien-Po
;
Suzuki, Yuta
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Suzuki, Yuta
;
Gullickson, Donald
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Gullickson, Donald
;
Ahmad, Raheel
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Ahmad, Raheel
;
Kokona, Bashkim
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Kokona, Bashkim
;
Fairman, Robert
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Fairman, Robert
;
Cheng, Richard P.
论文数:
0
引用数:
0
h-index:
0
机构:
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA
Cheng, Richard P.
.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,
2006,
128
(49)
:15556
-15557
[6]
Anticancer α-helical peptides and structure/function relationships underpinning their interactions with tumour cell membranes
[J].
Dennison, Sarah R.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Dennison, Sarah R.
;
Whittaker, Michelle
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Whittaker, Michelle
;
Harris, Frederick
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Harris, Frederick
;
Phoenix, David A.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Univ Cent Lancashire, Fac Sci, Preston PR1 2HE, Lancs, England
Phoenix, David A.
.
CURRENT PROTEIN & PEPTIDE SCIENCE,
2006,
7
(06)
:487
-499
[7]
The introduction of fluorine atoms or trifluoromethyl groups in short cationic peptides enhances their antimicrobial activity
[J].
Gimenez, Diana
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Gimenez, Diana
;
Andreu, Cecilia
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Andreu, Cecilia
;
del Olmo, Marcel-li
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
del Olmo, Marcel-li
;
Varea, Teresa
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Varea, Teresa
;
Diaz, Dolores
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Valencia, Fac Farm, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain
Diaz, Dolores
;
论文数:
引用数:
h-index:
机构:
Asensio, Gregorio
.
BIOORGANIC & MEDICINAL CHEMISTRY,
2006,
14
(20)
:6971
-6978
[8]
MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain
[J].
Hallock, KJ
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Hallock, KJ
;
Lee, DK
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Lee, DK
;
Ramamoorthy, A
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Ramamoorthy, A
.
BIOPHYSICAL JOURNAL,
2003,
84
(05)
:3052
-3060
[9]
Cytotoxic and allergenic potential of bioactive proteins and peptides
[J].
Hartmann, Rainer
论文数:
0
引用数:
0
h-index:
0
机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Hartmann, Rainer
;
Wal, Jean-Michel
论文数:
0
引用数:
0
h-index:
0
机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Wal, Jean-Michel
;
Bernard, Herve
论文数:
0
引用数:
0
h-index:
0
机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Bernard, Herve
;
Pentzien, Anne-Kathrin
论文数:
0
引用数:
0
h-index:
0
机构:
Fed Dairy Res Ctr, Inst Dairy Chem & Technol, D-24121 Kiel, Germany
Pentzien, Anne-Kathrin
.
CURRENT PHARMACEUTICAL DESIGN,
2007,
13
(09)
:897
-920
[10]
Modulating protein structure with fluorous amino acids: Increased stability and native-like structure conferred on a 4-helix bundle protein by hexafluoroleucine
[J].
Lee, HY
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Lee, HY
;
Lee, KH
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Lee, KH
;
Al-Hashimi, HM
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Al-Hashimi, HM
;
Marsh, ENG
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA
Marsh, ENG
.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,
2006,
128
(01)
:337
-343
←
1
2
3
4
→