Quantification of Absolute Myocardial Blood Flow by Magnetic Resonance Perfusion Imaging

被引：55
作者：
Lee, Daniel C.
Johnson, Nils P.
机构：
[1] Northwestern Univ, Feinberg Sch Med, Feinberg Cardiovasc Res Inst, Dept Med, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Div Cardiol, Bluhm Cardiovasc Inst, Chicago, IL 60611 USA
来源：
JACC-CARDIOVASCULAR IMAGING | 2009年 / 2卷 / 06期
关键词：
blood flow quantification; cardiac magnetic resonance; gadolinium; myocardial perfusion; quantitative modeling; CORONARY-ARTERY-DISEASE; 1ST-PASS MR PERFUSION; COMPUTED-TOMOGRAPHY; NONINVASIVE DETECTION; TRANSMURAL PERFUSION; ASYMPTOMATIC ADULTS; STRESS PERFUSION; TRANSIT-TIME; RESERVE; ATHEROSCLEROSIS;
D O I：
10.1016/j.jcmg.2009.04.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
By serially imaging the myocardium during the initial transit of gadolinium contrast, magnetic resonance perfusion imaging can accurately assess relative reductions in regional myocardial blood flow and identify hemodynamically significant coronary artery disease. Models can be used to quantify myocardial blood flow (in milliliters/minute/gram) on the basis of dynamic signal changes within the myocardium and left ventricular cavity. Although the mathematical modeling involved in this type of analysis adds complexity, the benefits of absolute blood flow quantification might improve clinical diagnosis and have important implications for cardiovascular research. (J Am Coll Cardiol Img 2009;2:761-70) (C) 2009 by the American College of Cardiology Foundation
引用
收藏
页码：761 / 770
页数：10
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