Testing Susceptibility of Multidrug-Resistant Mycobacterium tuberculosis to Second-Line Drugs by Use of Blood Agar

被引：10

作者：

Satana, Dilek ^{[2
]}

Coban, Ahmet Yilmaz ^{[1
]}

Uzun, Meltem ^{[2
]}

机构：

[1] Ondokuz Mayis Univ, Sch Med, Dept Microbiol & Clin Microbiol, TR-55139 Samsun, Turkey

[2] Istanbul Univ, Istanbul Med Sch, Dept Microbiol & Clin Microbiol, Istanbul, Turkey

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2010年 / 48卷 / 11期

关键词：

D O I：

10.1128/JCM.00688-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In this study, the susceptibilities of 35 multidrug-resistant (MDR) Mycobacterium tuberculosis clinical isolates to second-line drugs, including kanamycin (KM), rifabutin (RBU), ofloxacin (OFX), p-aminosalicylic acid (PAS), capreomycin (CAP), clofazimine (CFM), and ethionamide (ETH), were investigated on blood agar according to CLSI recommendations. Compared with the results of the Bactec 460 TB system, agreement was 100, 100, 97, 100, 100, 100, and 86% for KM, RBU, OFX, PAS, CAP, CFM, and ETH, respectively. Compared with the results of the proportion method, agreement was 100, 100, 97, 100, 97, 100, and 77% for KM, RBU, OFX, PAS, CAP, CFM, and ETH, respectively.

引用

页码：4291 / 4293

页数：3

共 22 条

[1]

[Anonymous], 2003, Susceptibility Testing of Mycobacteria, Nocardiae, and Other Aerobic Actinomycetes

[2]

Approved Standard. NCCLS document M24-A. NCCLS, 940 West Valley Road

[3] Evaluation of blood agar for susceptibility testing of Mycobacterium tuberculosis against first-line antituberculous drugs:: Results from two centers [J].

Coban, A. Y. ;

Martin, A. ;

Uzun, M. ;

Bilgin, K. ;

Palomino, J. C. ;

Durupinar, B. .

JOURNAL OF CHEMOTHERAPY, 2008, 20 (03) :388-390

[4] Comparative Study for Determination of Mycobacterium tuberculosis Susceptibility to First- and Second-Line Antituberculosis Drugs by the Etest Using 7H11, Blood, and Chocolate Agar [J].

Coban, Ahmet Yilmaz ;

Bilgin, Kemal ;

Uzun, Meltem ;

Akgunes, Alper ;

Yusof, Anne ;

Durupinar, Belma .

JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 46 (12) :4095-4098

[5]

Coban AY, 2006, INT J TUBERC LUNG D, V10, P450

[6] Susceptibilities of Mycobacterium tuberculosis to isoniazid and rifampin on blood agar [J].

Coban, AY ;

Bilgin, K ;

Uzun, M ;

Fisgin, NT ;

Akgunes, A ;

Cihan, CC ;

Birinci, A ;

Durupinar, B .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (04) :1930-1931

[7]

Della-Latta P, 1998, ESSENTIAL PROCEDURES, P169

[8] Blood agar and Mycobacterium tuberculosis:: the end of a dogma [J].

Drancourt, M ;

Carrieri, P ;

Gévaudan, MJ ;

Raoult, D .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (04) :1710-1711

[9] Cost-Effectiveness of Blood Agar for Isolation of Mycobacteria [J].

Drancourt, Michel ;

Raoult, Didier .

PLOS NEGLECTED TROPICAL DISEASES, 2007, 1 (02)

[10]

Inderlied C.B., 1996, Antibiotics in laboratory medicine, V4th, P127

← 1 2 3 →