Microsensor-aided measurements measurements of cellular signalling and metabolism on tumor cells -: The cell monitoring system (CMS®)

被引：14

作者：

Wolf, B ^{[1
]}

Brischwein, M ^{[1
]}

Baumann, W ^{[1
]}

Ehret, R ^{[1
]}

Henning, T ^{[1
]}

Lehmann, M ^{[1
]}

Schwinde, A ^{[1
]}

机构：

[1] Univ Freiburg, Inst Immunobiol, AG Med Phys & Electron Microscopy, D-79104 Freiburg, Germany

来源：

TUMOR BIOLOGY | 1998年 / 19卷 / 05期

关键词：

biosensors; cellular; signal transduction; therapy; tumor; PhysioControl-Microsystem;

D O I：

10.1159/000030030

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Microsensors provide instruments particularly suited for the rapid, noninvasive and on-line analysis of cell and tissue cultures. The microsensor system presented in this paper is a modular arrangement of various planar and nonplanar sensor elements for the measurement of physiological parameters of cell cultures. An optic access to the cultures (e.g. for light microscopy and spectrophotometric techniques) is also provided for a parallel and comparative data acquisition. The system was originally designed for biomedical research in chemotherapy (predicative chemotherapy assays) and pharmacology but it turned out to be also an effective tool for toxicological and environmental research.

引用

页码：374 / 383

页数：10

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