Brain aging: lessons from community studies

被引:23
作者
Fratiglioni, Laura [1 ]
Mangialasche, Francesca [1 ]
Qiu, Chengxuan [1 ]
机构
[1] Karolinska Inst, Aging Res Ctr, S-11330 Stockholm, Sweden
基金
瑞典研究理事会;
关键词
brain aging; dementia; dietary factors; nutrition; prevention; BODY-MASS INDEX; CARDIOVASCULAR RISK-FACTORS; INCIDENT ALZHEIMER-DISEASE; TOTAL CHOLESTEROL LEVELS; FOLLOW-UP DATA; LATE-LIFE; DIABETES-MELLITUS; COGNITIVE IMPAIRMENT; MEDITERRANEAN DIET; VITAMIN-E;
D O I
10.1111/j.1753-4887.2010.00353.x
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Dementia is an acquired highly disabling syndrome common among elderly people. Alzheimer's disease is the most frequent type of dementia, and its prevalence is rapidly increasing due to the aging of populations. Therefore, the need to find effective preventive means is pressing. Population studies allow identification of risk/protective factors for dementia/Alzheimer's disease, thus leading to preventive strategies that can be implemented in the general population to reduce the incidence of this disorder. Presented here is an overview of the main findings of epidemiological studies on nutritional factors and nutrition-related pathological conditions, as related to dementia and Alzheimer's disease.
引用
收藏
页码:S119 / S127
页数:9
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[91]   Vascular risk factors and dementia How to move forward? [J].
Viswanathan, Anand ;
Rocca, Walter A. ;
Tzourio, Christophe .
NEUROLOGY, 2009, 72 (04) :368-374
[92]   Personality and lifestyle in relation to dementia incidence [J].
Wang, H. -X. ;
Karp, A. ;
Herlitz, A. ;
Crowe, M. ;
Kareholt, I. ;
Winblad, B. ;
Fratiglioni, L. .
NEUROLOGY, 2009, 72 (03) :253-259
[93]   Vitamin B12 and folate in relation to the development of Alzheimer's disease [J].
Wang, HX ;
Wahlin, A ;
Basun, H ;
Fastbom, J ;
Winblad, B ;
Fratiglioni, L .
NEUROLOGY, 2001, 56 (09) :1188-1194
[94]   Body Adiposity in Late Life and Risk of Dementia or Cognitive Impairment in a Longitudinal Community-Based Study [J].
West, Nancy A. ;
Haan, Mary N. .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2009, 64 (01) :103-109
[95]   Midlife cardiovascular risk factors and risk of dementia in late life [J].
Whitmer, RA ;
Sidney, S ;
Selby, J ;
Johnston, SC ;
Yaffe, K .
NEUROLOGY, 2005, 64 (02) :277-281
[96]   Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study [J].
Whitmer, RA ;
Gunderson, EP ;
Barrett-Connor, E ;
Quesenberry, CP ;
Yaffe, K .
BMJ-BRITISH MEDICAL JOURNAL, 2005, 330 (7504) :1360-1362B
[97]   The effect of borderline diabetes on the risk of dementia and Alzheimer's disease [J].
Xu, Weili ;
Qiu, Chengxuan ;
Winblad, Bengt ;
Fratiglioni, Laura .
DIABETES, 2007, 56 (01) :211-216
[98]   Mid- and Late-Life Diabetes in Relation to the Risk of Dementia A Population-Based Twin Study [J].
Xu, Weili ;
Qiu, Chengxuan ;
Gatz, Margaret ;
Pedersen, Nancy L. ;
Johansson, Boo ;
Fratiglioni, Laura .
DIABETES, 2009, 58 (01) :71-77
[99]   Diabetes mellitus and risk of dementia in the Kungsholmen project -: A 6-year follow-up study [J].
Xu, WL ;
Qiu, CX ;
Wahlin, Å ;
Winblad, B ;
Fratiglioni, L .
NEUROLOGY, 2004, 63 (07) :1181-1186
[100]   Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements - The Cache County Study [J].
Zandi, PP ;
Anthony, JC ;
Khachaturian, AS ;
Stone, SV ;
Gustafson, D ;
Tschanz, JT ;
Norton, MC ;
Welsh-Bohmer, KA ;
Breitner, JCS .
ARCHIVES OF NEUROLOGY, 2004, 61 (01) :82-88