Nickel-catalyzed ring-opening of α-hydroxycyclobutenones with a remarkable ligand effect

被引：8

作者：

Gao, Songsong ^{[1
]}

Hu, Xiangdong ^{[1
]}

机构：

[1] Northwest Univ, Minist Educ China, Key Lab Synthet & Nat Funct Mol Chem, Sch Chem & Mat Sci, Xian 710127, Shaanxi, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 76期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

C-C BOND; CONROTATORY ELECTROCYCLIC REACTIONS; CYCLOBUTENONE REARRANGEMENTS; STEREOSELECTIVE-SYNTHESIS; INWARD TORQUOSELECTIVITY; ORGANIC-SYNTHESIS; TETRONIC ACIDS; PULVINIC ACID; LEWIS-ACID; SUBSTITUENT;

D O I：

10.1039/c7cc03340k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Ni-catalyzed ring-opening of alpha-hydroxycyclobutenones is reported herein. A remarkable ligand effect was observed during transformations following the ring-opening. The employment of PPh3 leads to the formation of 2-furanones 2 through a migration of an alkoxyl group, and 2-furanones 3 were generated through a migration of hydrogen in the presence of Xantphos, affording a divergent approach to 2-furanones bearing multiple functional groups.

引用

页码：10540 / 10543

页数：4

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