Physiological Effects of Wearing N95 Respirator on Medical Staff During Prolong Work Hours in Covid-19 Departments

被引：5
作者：
Shechtman, Liran [1 ,2 ]
Ben-Haim, Gal [2 ,3 ]
Ben-Zvi, Ilan [1 ,2 ]
Steel, Laurence [2 ,3 ]
Ironi, Avinoah [2 ,3 ]
Huszti, Ella [4 ]
Chatterji, Sumit [2 ,5 ]
Levy, Liran [2 ,5 ]
机构：
[1] Sheba Med Ctr, Internal Med Dept, Tel Hashomer, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
[3] Sheba Med Ctr, Dept Emergency Med, Tel Hashomer, Israel
[4] Univ Toronto, Univ Hlth Network, Biostat Res Unit, Toronto, ON, Canada
[5] Sheba Med Ctr, Inst Pulm Med, Tel Hashomer, Israel
来源：
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2022年 / 64卷 / 06期
关键词：
N95; respirator; physiological effects; SARS CoV 2; ED; emergency department; EtCO2; end tidal carbon dioxide; HR; heart rate; IQR; interquartile range; PPE; personal protective equipment; PvCO2; partial pressure of carbon dioxide in mixed venous blood; PvO2; partial pressure of oxygen tension in mixed venous blood; severe acute respiratory syndrome coronavirus 2; CARE; INFECTION; IMPACT; MASKS;
D O I：
10.1097/JOM.0000000000002542
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objective The objective of the current study was to determine gas exchange abnormalities and physiological changes among healthcare workers during a 4-hour emergency department (ED) shift while wearing the N95 respirator. Methods Single-center prospective observational study. Comparisons of paired measurements were performed using a non-parametric Wilcoxon matched-pairs signed-rank test. Results: Forty-one subjects were included. Prolonged N95 respirator use was associated with a significant decline in plasma pH (7.35 mmHg vs 7.34 mmHg, P = 0.02), PvO(2) (23.2 mmHg vs 18.6 mmHg, P < 0.001) and a concurrent increase in EtCO2 (32.5 mmHg vs 38.5 mmHg, P < 0.0001). PvCO(2) and bicarbonate levels did not differ. No significant change was observed for heart rate or oxygen saturation. Conclusion Using an N95 respirator for prolonged periods by healthcare professionals may provoke changes in gas exchange. The clinical significance of these changes remains to be determined.
引用
收藏
页码：E378 / E380
页数：3
相关论文
共 16 条
  • [1] Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta-analysis
    Byrne, Anthony L.
    Bennett, Michael
    Chatterji, Robindro
    Symons, Rebecca
    Pace, Nathan L.
    Thomas, Paul S.
    [J]. RESPIROLOGY, 2014, 19 (02) : 168 - 175
  • [2] Return to training in the COVID-19 era: The physiological effects of face masks during exercise
    Epstein, Danny
    Korytny, Alexander
    Isenberg, Yoni
    Marcusohn, Erez
    Zukermann, Robert
    Bishop, Boaz
    Minha, Sa'ar
    Raz, Aeyal
    Miller, Asaf
    [J]. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 2021, 31 (01) : 70 - 75
  • [3] Face Masks and the Cardiorespiratory Response to Physical Activity in Health and Disease
    Hopkins, Susan R.
    Dominelli, Paolo B.
    Davis, Christopher K.
    Guenette, Jordan A.
    Luks, Andrew M.
    Molgat-Seon, Yannick
    Sa, Rui Carlos
    Sheel, A. William
    Swenson, Erik R.
    Stickland, Michael K.
    [J]. ANNALS OF THE AMERICAN THORACIC SOCIETY, 2021, 18 (03) : 399 - 407
  • [4] Short-term skin reactions following use of N95 respirators and medical masks
    Hua, Wei
    Zuo, Ying
    Wan, Ruoyu
    Xiong, Lidan
    Tang, Jie
    Zou, Lin
    Shu, Xiaohong
    Li, Li
    [J]. CONTACT DERMATITIS, 2020, 83 (02) : 115 - 121
  • [5] Kao TW, 2004, J FORMOS MED ASSOC, V103, P624
  • [6] Effects of Intermittent Hypoxia on Pulmonary Vascular and Systemic Diseases
    Kimura, Hiroshi
    Ota, Hiroyo
    Kimura, Yuya
    Takasawa, Shin
    [J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2019, 16 (17)
  • [7] Possible Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Public Bath Center in Huai'an, Jiangsu Province, China
    Luo, Chao
    Yao, Lun
    Zhang, Li
    Yao, Mengchu
    Chen, Xiaofei
    Wang, Qilong
    Shen, Hongbing
    [J]. JAMA NETWORK OPEN, 2020, 3 (03) : E204583
  • [8] Efficacy of face masks and respirators in preventing upper respiratory tract bacterial colonization and co-infection in hospital healthcare workers - Authors' reply
    MacIntyre, C. Raina
    Wang, Quanyi
    Rahman, Bayzidur
    Seale, Holly
    Ridda, Iman
    Gao, Zhanhai
    Yang, Peng
    Shi, Weixian
    Pang, Xinghuo
    Zhang, Yi
    Moa, Aye
    [J]. PREVENTIVE MEDICINE, 2014, 65 : 154 - 154
  • [9] The efficacy of medical masks and respirators against respiratory infection in healthcare workers
    MacIntyre, Chandini Raina
    Chughtai, Abrar Ahmad
    Rahman, Bayzidur
    Peng, Yang
    Zhang, Yi
    Seale, Holly
    Wang, Xiaoli
    Wang, Quanyi
    [J]. INFLUENZA AND OTHER RESPIRATORY VIRUSES, 2017, 11 (06) : 511 - 517
  • [10] Mask-associated 'de novo' headache in healthcare workers during the COVID-19 pandemic
    Ramirez-Moreno, Jose Maria
    Ceberino, David
    Gonzalez Plata, Alberto
    Rebollo, Belen
    Macias Sedas, Pablo
    Hariramani, Roshan
    Roa, Ana M.
    Constantino, Ana B.
    [J]. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2021, 78 (08) : 548 - 554
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