Can adenosine triphosphate be a proxy measure in evaluation of hand disinfection effect?

被引：0

作者：

Breidablik, H. J. ^{[1
]}

Lysebo, D. E. ^{[4
]}

Johannesen, L. ^{[2
]}

Skare, A. ^{[5
]}

Andersen, J. R. ^{[3
]}

Kleiven, O. T. ^{[3
]}

机构：

[1] Helse Forde HF, Forde, Norway

[2] Thelma Indoor Air & Working Environm AS, Microbiol Dept, Trondheim, Norway

[3] Norway Univ Appl Sci, Fac Western, Forde, Norway

[4] Haukeland Hosp, Bergen, Norway

[5] Forde Hosp Trust, Dept Infect Control, Forde, Norway

来源：

JOURNAL OF HOSPITAL INFECTION | 2020年 / 105卷 / 03期

关键词：

Adenosine triphosphate; Disinfection; Hand hygiene; Infection control nursing; SURFACES; BIOLUMINESCENCE;

D O I：

10.1016/j.jhin.2020.04.043

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Contaminated hands may contribute to the transmission of pathogens. In the prevention of healthcare-associated infections the effect of disinfection methods should ideally be possible to measure in a simple way. Microbial cultivation is the reference standard, but it is a rather complicated and time-consuming procedure, and the use of swabs for measuring adenosine triphosphate (ATP) has become a much-used proxy measurement (bioluminescence). We evaluated the effect of three hand-disinfection methods on eradication of Escherichia coli from artificially contaminated hands, using cultivation and ATP measurements in parallel. ATP measurement was found to be an unsuitable method as this reflects the total amount of biomaterial present left on the hands, not only the viable bacteria. (C) 2020 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：558 / 560

页数：3

共 10 条

[1] Use of ATP bioluminescence for assessing the cleanliness of hospital surfaces: A review of the published literature (1990-2012) [J].