The Mobile Phase Motion in Ascending Micellar Thin-Layer Chromatography with Normal-Phase Plates

被引：5
作者：
Boichenko, Alexander P. [1 ]
Makhno, Iryna V. [3 ]
Renkevich, Anton Yu. [2 ]
Loginova, Lidia P. [2 ]
机构：
[1] Univ Groningen, Univ Ctr Pharm, Dept Analyt Biochem, NL-9713 AV Groningen, Netherlands
[2] Kharkov VN Karazin Natl Univ, Dept Chem Metrol, UA-61077 Kharkov, Ukraine
[3] Kharkov Pharmaceut Plant Zdorove Narodu Co Ltd, UA-61013 Kharkov, Ukraine
来源：
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC | 2011年 / 24卷 / 06期
关键词：
Micellar thin-layer chromatography; Viscosity; Surface tension; Motion; Model; ALIPHATIC CARBOXYLIC-ACIDS; LIQUID-CHROMATOGRAPHY; PAPER CHROMATOGRAPHY; HYDROPHILIC VITAMINS; LOW VOLATILITY; FLOW VELOCITY; AMINO-ACIDS; SEPARATION; SURFACTANTS; MIGRATION;
D O I：
10.1556/JPC.24.2011.6.2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The physical chemical characteristics (surface tension and viscosity) of micellar mobile phases based on the cationic surfactant cetylpiridinium chloride and additives of alcohols (ethanol, 1-propanol, 1-butanol, 1-pentanol) have been obtained in this work. The effect of mobile phase properties on the motion of mobile phase in the ascending mode of thin-layer chromatography (TLC) was investigated. The applicability of a quadratic relationship between the time of mobile phase motion and the distance from the solvent entry position of mobile phase and front of the mobile phase was validated for micellar TLC. It was observed that the retardation factors of hydrophilic test compounds change significantly only at low contents of the modifier in micellar mobile phase.
引用
收藏
页码：463 / 469
页数：7
相关论文
共 50 条
  • [1] The Mobile Phase Motion in Ascending Micellar Thin-Layer Chromatography with Normal-Phase Plates
    Alexander P. Boichenko
    Iryna V. Makhno
    Anton Yu. Renkevich
    Lidia P. Loginova
    JPC – Journal of Planar Chromatography – Modern TLC, 2011, 24 : 463 - 469
  • [2] Normal-phase thin-layer chromatography of some angiotensin converting enzyme (ACE) inhibitors and their metabolites
    Odovic, Jadranka
    Aleksic, Mirjana
    Stojimirovic, Biljana
    Milojkovic-Opsenica, Dusanka
    Tesic, Zivoslav
    JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2009, 74 (06) : 677 - 688
  • [3] Quantitative structure-retardation factor relationship of protein amino acids in different solvent mixtures for normal-phase thin-layer chromatography
    Yousefinejad, Saeed
    Honarasa, Fatemeh
    Saeed, Negar
    JOURNAL OF SEPARATION SCIENCE, 2015, 38 (10) : 1771 - 1776
  • [4] Selectivity in normal-phase liquid chromatography with binary mobile phase
    Borowko, Malgorzata
    Oscik-Mendyk, Barbara
    ADSORPTION-JOURNAL OF THE INTERNATIONAL ADSORPTION SOCIETY, 2010, 16 (4-5): : 397 - 403
  • [5] Thin-Layer Chromatography of Some Amino Acids on Silica in Aqueous-Organic and Modified Micellar Mobile Phases
    Shtykov, S. N.
    Sumina, E. G.
    Uglanova, V. Z.
    Sorokina, O. N.
    JOURNAL OF ANALYTICAL CHEMISTRY, 2017, 72 (08) : 870 - 878
  • [6] Thin-layer chromatography of aflatoxins and zearalenones with β-cyclodextrins as mobile phase additives
    Larionova, D. A.
    Goryacheva, I. Y.
    Van Peteghem, C.
    De Saeger, S.
    WORLD MYCOTOXIN JOURNAL, 2011, 4 (02) : 113 - 117
  • [7] Micellar Thin-Layer Chromatography and Preconcentration of L-Carnitine with Magnetite Nanoparticles
    Sumina, E. G.
    Shtykov, S. N.
    Reshetnikova, I. S.
    Yurasov, N. A.
    Uglanova, V. Z.
    JOURNAL OF ANALYTICAL CHEMISTRY, 2022, 77 (08) : 993 - 999
  • [8] Dimethyl Carbonate as a Mobile-Phase Modifier for Normal-Phase and Hydrophilic Interaction Liquid Chromatography
    Boes, Philip D.
    Elleman, Sophie R.
    Danielson, Neil D.
    SEPARATIONS, 2023, 10 (02)
  • [9] Quantitative Structure-Retention Relationship Modeling of the Retention Behavior of Selected Antipsychotic Drugs in Normal-Phase Thin-Layer Chromatography
    Ciura, Krzesimir
    Rutecka, Anna
    Kawczak, Piotr
    Nowakowska, Joanna
    JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC, 2017, 30 (03) : 225 - 230
  • [10] Thin-layer chromatography of some amino acids on silica in aqueous–organic and modified micellar mobile phases
    S. N. Shtykov
    E. G. Sumina
    V. Z. Uglanova
    O. N. Sorokina
    Journal of Analytical Chemistry, 2017, 72 : 870 - 878
12345