A random signal model for cDNA microarrays

被引：0

作者：

Balagurunathan, Y ^{[1
]}

Dougherty, ER ^{[1
]}

Chen, YD ^{[1
]}

Bittner, ML ^{[1
]}

Trent, JM ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Elect Engn, College Stn, TX 77843 USA

来源：

MICROARRAYS: OPTICAL TECHNOLOGIES AND INFORMATICS | 2001年 / 4266卷

关键词：

random model; simulated cDNA microarray; cDNA spot model;

D O I：

10.1117/12.427985

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The images resulting from cDNA microarrays are highly random. There are many aspects to this randomness, including spot size, shape, intensity, uniformity, and circularity, as well as both foreground and background noise. This paper presents a random model for the generation of microrarray images. The model is complicated and contains over twenty parameters. It can be used to test microarray imaging algorithms and to simulate the effects of various dependencies within the image formation process.

引用

页码：163 / 170

页数：8

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