Enlarged Vestibular Aqueduct: Review of Controversial Aspects

被引：86

作者：

Gopen, Quinton ^{[1
]}

Zhou, Guangwei ^{[2
]}

Whittemore, Kenneth ^{[2
]}

Kenna, Margaret ^{[2
]}

机构：

[1] UCLA Med Ctr, Div Head & Neck Surg, Los Angeles, CA 90095 USA

[2] Harvard Univ, Sch Med, Dept Otolaryngol & Commun Enhancement, Childrens Hosp Boston, Boston, MA USA

来源：

LARYNGOSCOPE | 2011年 / 121卷 / 09期

关键词：

Cranial base; otology; pediatric ears/otology; vestibular; SENSORINEURAL HEARING-LOSS; COCHLEAR IMPLANTATION; PENDRED-SYNDROME; ENDOLYMPHATIC DUCT; STEROID TREATMENT; TEMPORAL BONE; SLC26A4; GENE; CHILDREN; MUTATIONS; DEAFNESS;

D O I：

10.1002/lary.22083

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Objectives: To review the controversial aspects of the enlarged vestibular aqueduct syndrome. Study Design: Contemporary review. Methods: A literature search using the terms "enlarged vestibular aqueduct and large vestibular aqueduct" were used to generate the articles for review in this article. Results: The enlarged vestibular aqueduct is a condition causing variable auditory and vestibular dysfunction. Although it has been 32 years since Valvasorri and Clemis recognized the clinical importance of the enlarged vestibular aqueduct, many controversial aspects of the diagnosis remain. The topics reviewed in this discussion are as follows: size criteria for radiographic diagnosis, precipitating factors for hearing loss, corticosteroid treatment and sac surgery, conductive component to hearing loss, natural progression of hearing loss, correlations between aqueduct size and hearing loss, genetics, vestibular symptoms, and theories regarding mechanisms behind the symptoms. Conclusion: The enlarged vestibular aqueduct remains a controversial entity with variable presentation, progression, and prognosis.

引用

页码：1971 / 1978

页数：8

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