Kaposiform Hemangioendothelioma With Kasabach-Merritt Syndrome: A New Indication for Propranolol Treatment

被引：52

作者：

Hermans, Denise Josephina Johanna ^{[1
]}

van Beynum, Ingrid Mathilde ^{[2
]}

van der Vijver, Rozemarijn Junelle ^{[3
]}

Kool, Leonardus Jan Schultze ^{[4
]}

de Blaauw, Ivo ^{[3
]}

van der Vleuten, Catharina Joanna Maria ^{[1
]}

机构：

[1] Radboud Univ Nijmegen Med Ctr, Dept Dermatol, NL-6500 HB Nijmegen, Netherlands

[2] Radboud Univ Nijmegen Med Ctr, Dept Pediat, NL-6500 HB Nijmegen, Netherlands

[3] Radboud Univ Nijmegen Med Ctr, Dept Pediat Surg, NL-6500 HB Nijmegen, Netherlands

[4] Radboud Univ Nijmegen Med Ctr, Dept Intervent Radiol, NL-6500 HB Nijmegen, Netherlands

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2011年 / 33卷 / 04期

关键词：

hemangioendothelioma; Kasabach-Merritt syndrome; beta-blocker; propranolol; vincristine; VINCRISTINE; HEMANGIOMAS;

D O I：

10.1097/MPH.0b013e3182152e4e

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Kaposiform hemangioendothelioma is a rare vascular tumor in children. Especially, in association with the Kasabach-Merritt Phenomenon it can be life threatening. The management of these patients is very difficult and an aggressive treatment regime is required. Several multimodality and chemotherapeutic regimens have been described but with variable success and many side effects. We present a 6-week-old boy with Kaposiform hemangioendothelioma and Kasabach-Merritt Phenomenon. Ongoing propranolol treatment with only 4 initial courses of vincristine resulted in a remission that lasted at least 1 year.

引用

页码：E171 / E173

页数：3

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