Carbon dots for multiphoton bioimaging

被引:1909
作者
Cao, Li
Wang, Xin
Meziani, Mohammed J.
Lu, Fushen
Wang, Haifang
Luo, Pengju G.
Lin, Yi
Harruff, Barbara A.
Veca, L. Monica
Murray, Davoy
Xie, Su-Yuan
Sun, Ya-Ping [1 ]
机构
[1] Clemson Univ, Dept Chem, Clemson, SC 29634 USA
[2] Clemson Univ, Lab Emerging Mat & Technol, Clemson, SC 29634 USA
关键词
D O I
10.1021/ja073527l
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Carbon nanoparticles upon simple surface passivation exhibit bright photoluminescence. Reported here is a new finding that these carbon dots are also strongly two-photon luminescent with pulsed laser excitation in the near-infrared. The experimentally measured two-photon absorption cross-sections are comparable to those of the high-performance semiconductor quantum dots already available in the literature. The two-photon luminescence microscopy imaging of human breast cancer cells with internalized carbon dots is demonstrated.
引用
收藏
页码:11318 / +
页数:3
相关论文
共 18 条
[1]   Two-photon tissue imaging: Seeing the immune system in a fresh light [J].
Cahalan, MD ;
Parker, I ;
Wei, SH ;
Miller, MJ .
NATURE REVIEWS IMMUNOLOGY, 2002, 2 (11) :872-880
[2]   Upconversion luminescence from CdSe nanoparticles [J].
Chen, W ;
Joly, AG ;
McCready, DE .
JOURNAL OF CHEMICAL PHYSICS, 2005, 122 (22)
[3]   In vivo cancer targeting and imaging with semiconductor quantum dots [J].
Gao, XH ;
Cui, YY ;
Levenson, RM ;
Chung, LWK ;
Nie, SM .
NATURE BIOTECHNOLOGY, 2004, 22 (08) :969-976
[4]   Ensemble and single particle photophysical proper-ties (Two-Photon excitation, anisotropy, FRET, lifetime, spectral conversion) of commercial quantum dots in solution and in live cells [J].
Grecco, HE ;
Lidke, KA ;
Heintzmann, R ;
Lidke, DS ;
Spagnuolo, C ;
Martinez, OE ;
Jares-Erijman, EA ;
Jovin, TM .
MICROSCOPY RESEARCH AND TECHNIQUE, 2004, 65 (4-5) :169-179
[5]   Deep tissue two-photon microscopy [J].
Helmchen, F ;
Denk, W .
NATURE METHODS, 2005, 2 (12) :932-940
[6]  
Larson DR, 2003, SCIENCE, V300, P1434, DOI 10.1126/science.1083780
[7]   RNA polymer translocation with single-walled carbon nanotubes [J].
Lu, Q ;
Moore, JM ;
Huang, G ;
Mount, AS ;
Rao, AM ;
Larcom, LL ;
Ke, PC .
NANO LETTERS, 2004, 4 (12) :2473-2477
[8]   Frequency degenerate and nondegenerate two-photon absorption spectra of semiconductor quantum dots [J].
Padilha, L. A. ;
Fu, J. ;
Hagan, D. J. ;
Van Stryland, E. W. ;
Cesar, C. L. ;
Barbosa, L. C. ;
Cruz, C. H. B. ;
Buso, D. ;
Martucci, A. .
PHYSICAL REVIEW B, 2007, 75 (07)
[9]   The empirical correlation between size and two-photon absorption cross section of CdSe and CdTe quantum dots [J].
Pu, Shih-Chieh ;
Yang, Meng-Ju ;
Hsu, Cheng-Chih ;
Lai, Chih-Wei ;
Hsieh, Cheng-Chih ;
Lin, Sheng Hsien ;
Cheng, Yi-Ming ;
Chou, Pi-Tai .
SMALL, 2006, 2 (11) :1308-1313
[10]   Rapid and effective labeling of brain tissue using TAT-conjugated CdS: Mn/ZnS quantum dots [J].
Santra, S ;
Yang, H ;
Stanley, JT ;
Holloway, PH ;
Moudgil, BM ;
Walter, G ;
Mericle, RA .
CHEMICAL COMMUNICATIONS, 2005, (25) :3144-3146