Factors Associated with Left Ventricular Function Recovery in Patients with Atrial Fibrillation Related Cardiomyopathy

被引:0
作者
Marcusohn, Erez [1 ]
Postnikov, Maria [1 ]
Kobo, Ofer [3 ]
Hellman, Yaron [1 ]
Mutlak, Diab [1 ]
Epstein, Danny [2 ]
Agmon, Yoram [1 ,4 ]
Gepstein, Lior [1 ,4 ]
Zukermann, Robert [1 ]
机构
[1] Rambam Hlth Care Campus, Dept Cardiol, IL-31096 Haifa, Israel
[2] Rambam Hlth Care Campus, Intens Care Unit, Haifa, Israel
[3] Hillel Yaffe Med Ctr, Dept Cardiol, Hadera, Israel
[4] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel
来源
ISRAEL MEDICAL ASSOCIATION JOURNAL | 2022年 / 24卷 / 02期
关键词
atrial fibrillation (AFIB); atrial tachyarrhythmia; cardioversion; heart failure with reduced ejection fraction (HFrEF); tachycardia induced cardiomyopathy; TACHYCARDIA-INDUCED CARDIOMYOPATHY; CATHETER ABLATION; SYSTOLIC DYSFUNCTION; HEART-FAILURE; SINUS RHYTHM; CARDIOVERSION; REGRESSION; VOLUME; TRIAL;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The diagnosis of atrial fibrillation (AFIB) related cardiomyopathy relies on ruling out other causes for heart failure and on recovery of left ventricular (LV) function following return to sinus rhythm (SR). The pathophysiology underlying this pathology is multifactorial and not as completely known as the factors associated with functional recovery following the restoration of SR. Objectives: To identify clinical and echocardiographic factors associated with LV systolic function improvement following electrical cardioversion (CV) or after catheter ablation in patients with reduced ejection fraction (EF) related to AFIB and normal LV function at baseline. Methods: The study included patients with preserved EF at baseline while in SR whose LVEF had reduced while in AFIB and improved LVEF following CV. We compared patients who had improved LVEF to normal baseline to those who did not. Results: Eighty-six patients with AFIB had evidence of reduced LV systolic function and improved EF following return to SR. Fifty-five (64%) returned their EF to baseline. Patients with a history of ischemic heart disease (IHD), worse LV function, and larger LV size during AFIB were less likely to return to normal LV function. Multivariant analysis revealed that younger patients with slower ventricular response, a history of IHD, larger LV size, and more significant deterioration of LVEF during AFIB were less likely to recover their EF to baseline values. Conclusions: Patients with worse LV function and larger left ventricle during AFIB are less likely to return their baseline LV function following the restoration of sinus rhythm.
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页码:101 / 106
页数:6
相关论文
共 25 条
[1]   Catheter Ablation of Atrial Fibrillation in Patients With Left Ventricular Systolic Dysfunction A Systematic Review and Meta-Analysis [J].
Anselmino, Matteo ;
Matta, Mario ;
D'Ascenzo, Fabrizio ;
Bunch, T. Jared ;
Schilling, Richard J. ;
Hunter, Ross J. ;
Pappone, Carlo ;
Neumann, Thomas ;
Noelker, Georg ;
Fiala, Martin ;
Bertaglia, Emanuele ;
Frontera, Antonio ;
Duncan, Edward ;
Nalliah, Chrishan ;
Jais, Pierre ;
Weerasooriya, Rukshen ;
Kalman, Jon M. ;
Gaita, Fiorenzo .
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2014, 7 (06) :1011-U63
[2]   Outcomes in Atrial Fibrillation Patients With and Without Left Ventricular Hypertrophy When Treated With a Lenient Rate-Control or Rhythm-Control Strategy [J].
Badheka, Apurva O. ;
Shah, Neeraj ;
Grover, Peeyush M. ;
Patel, Nileshkumar J. ;
Chothani, Ankit ;
Mehta, Kathan ;
Singh, Vikas ;
Deshmukh, Abhishek ;
Savani, Ghanshyambhai T. ;
Rathod, Ankit ;
Panaich, Sidakpal S. ;
Patel, Nilay ;
Arora, Shilpkumar ;
Bhalara, Vipulkumar ;
Coffey, James O. ;
Mitrani, Raul D. ;
Halperin, Jonathan L. ;
Viles-Gonzalez, Juan F. .
AMERICAN JOURNAL OF CARDIOLOGY, 2014, 113 (07) :1159-1165
[3]   Hemodynamic effects of an irregular sequence of ventricular cycle lengths during atrial fibrillation [J].
Clark, DM ;
Plumb, VJ ;
Epstein, AE ;
Kay, GN .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (04) :1039-1045
[4]   Catheter Ablation of Atrial Fibrillation in Patients with Concomitant Left Ventricular Impairment: a Systematic Review of Efficacy and Effect on Ejection Fraction [J].
Ganesan, Anand N. ;
Nandal, Savvy ;
Lueker, Jakob ;
Pathak, Rajeev K. ;
Mahajan, Rajiv ;
Twomey, Darragh ;
Lau, Dennis H. ;
Sanders, Prashanthan .
HEART LUNG AND CIRCULATION, 2015, 24 (03) :270-280
[5]   Tachycardia mediated cardiomyopathy: Pathophysiology, mechanisms, clinical features and management [J].
Gupta, Shuchita ;
Figueredo, Vincent M. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2014, 172 (01) :40-46
[6]  
Hindricks G, 2020, EUR HEART J
[7]   A Randomized Controlled Trial of Catheter Ablation Versus Medical Treatment of Atrial Fibrillation in Heart Failure (The CAMTAF Trial) [J].
Hunter, Ross J. ;
Berriman, Thomas J. ;
Diab, Ihab ;
Kamdar, Ravindu ;
Richmond, Laura ;
Baker, Victoria ;
Goromonzi, Farai ;
Sawhney, Vinit ;
Duncan, Edward ;
Page, Stephen P. ;
Ullah, Waqas ;
Unsworth, Beth ;
Mayet, Jamil ;
Dhinoja, Mehul ;
Earley, Mark J. ;
Sporton, Simon ;
Schilling, Richard J. .
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2014, 7 (01) :31-38
[8]   A Randomized Trial to Assess Catheter Ablation Versus Rate Control in the Management of Persistent Atrial Fibrillation in Heart Failure [J].
Jones, David G. ;
Haldar, Shouvik K. ;
Hussain, Wajid ;
Sharma, Rakesh ;
Francis, Darrel P. ;
Rahman-Haley, Shelley L. ;
McDonagh, Theresa A. ;
Underwood, Richard ;
Markides, Vias ;
Wong, Tom .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (18) :1894-1903
[9]   Incidence of Primary, Dilated Rather Than Tachycardia-Induced Cardiomyopathy among Patients Presenting with New Onset Atrial Arrhythmia and Heart Failure with Reduced Ejection Fraction [J].
Kamran, Hayaan ;
Ganatra, Sarju ;
Formica, Philip ;
Shah, Sachin P. ;
Venesy, David M. ;
Patten, Richard D. .
JOURNAL OF CARDIAC FAILURE, 2019, 25 (08) :S82-S82
[10]   Pulmonary-vein isolation for atrial fibrillation in patients with heart failure [J].
Khan, Mohammed N. ;
Jais, Pierre ;
Cummings, Jennifer ;
Di Biase, Luigi ;
Sanders, Prashanthan ;
Martin, David O. ;
Kautzner, Josef ;
Hao, Steven ;
Themistoclakis, Sakis ;
Fanelli, Raffaele ;
Potenza, Domenico ;
Massaro, Raimondo ;
Wazni, Oussama ;
Schweikert, Robert ;
Saliba, Walid ;
Wang, Paul ;
Al-Ahmad, Amin ;
Beheiry, Salwa ;
Santarelli, Pietro ;
Starling, Randall C. ;
Dello Russo, Antonio ;
Pelargonio, Gemma ;
Brachmann, Johannes ;
Schibgilla, Volker ;
Bonso, Aldo ;
Casella, Michela ;
Raviele, Antonio ;
Haissaguerre, Michel ;
Natale, Andrea .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (17) :1778-1785