A new rhodamine-based chemosensor for Cu2+ and the study of its behaviour in living cells

被引：89
作者：
Huang, Liang [1 ,2 ]
Wang, Xiao [3 ]
Xie, Guoqiang [1 ,2 ]
Xi, Pinxian [1 ,2 ]
Li, Zhengpeng [1 ,2 ]
Xu, Min [1 ,2 ]
Wu, Yongjie [3 ]
Bai, Decheng [3 ]
Zeng, Zhengzhi [1 ,2 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China
[3] Lanzhou Univ, Pharmacol Lab GanSu Prov, Key Lab Preclin Study New Tradit Chinese Med, Lanzhou 730000, Peoples R China
来源：
DALTON TRANSACTIONS | 2010年 / 39卷 / 34期
关键词：
FLUORESCENT CHEMOSENSOR; AQUEOUS-MEDIA; CHEMODOSIMETER; IONS; HG2+; SELECTIVITY; CU(II); SENSOR; COPPER; PROBE;
D O I：
10.1039/c0dt00606h
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A new rhodamine-based chemosensor (L1) was synthesized, and it exhibits high sensitivity and selectivity for the copper cation over other commonly coexistent metal ions in aqueous solution. Upon the addition of Cu2+, the spirolactam ring of L1 was opened and a 1 : 1 metal-ligand complex was formed. Fluorescent imaging of Cu2+ in living cells is also successfully demonstrated.
引用
收藏
页码：7894 / 7896
页数：3
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