共 140 条
The dietary inflammatory index, obesity, type 2 diabetes, and cardiovascular risk factors and diseases
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Odjidja, Emmanuel Nene
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Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia

Scott, David
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Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia
Deakin Univ, Inst Phys Act & Nutr IPAN, Sch Exercise & Nutr Sci, Geelong, Vic, Australia Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia

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Hebert, James R.
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Univ South Carolina, Arnold Sch Publ Hlth, Canc Prevent & Control Program, Columbia, SC 29208 USA
Univ South Carolina, Dept Epidemiol & Biostat, Arnold Sch Publ Hlth, Columbia, SC 29208 USA
Connecting Hlth Innovat LLC, Dept Nutr, Columbia, SC USA Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia

Hodge, Allison
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Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia
Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia

de Courten, Barbora
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Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia
机构:
[1] Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Clayton, Vic, Australia
[2] Deakin Univ, Inst Phys Act & Nutr IPAN, Sch Exercise & Nutr Sci, Geelong, Vic, Australia
[3] Univ South Carolina, Arnold Sch Publ Hlth, Canc Prevent & Control Program, Columbia, SC 29208 USA
[4] Univ South Carolina, Dept Epidemiol & Biostat, Arnold Sch Publ Hlth, Columbia, SC 29208 USA
[5] Connecting Hlth Innovat LLC, Dept Nutr, Columbia, SC USA
[6] Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia
[7] Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia
关键词:
cardiovascular diseases;
diabetes;
dietary inflammatory index;
obesity;
METABOLIC SYNDROME;
CARDIOMETABOLIC RISK;
ADIPOSE-TISSUE;
NATIONAL-HEALTH;
INNATE IMMUNITY;
GUT MICROBIOTA;
HEART-DISEASE;
ASSOCIATION;
COMPONENTS;
MORTALITY;
D O I:
10.1111/obr.13349
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
An unhealthy diet is a recognized risk factor in the pathophysiology of numerous chronic noncommunicable diseases (NCD), including obesity, type 2 diabetes (T2DM), and cardiovascular diseases (CVD). This is, at least in part, due to unhealthy diets causing chronic low-grade inflammation in the gut and systemically. To characterize the inflammatory potential of diet, we developed the Dietary Inflammatory Index (DII (R)). Following this development, around 500 papers have been published, which examined the association between the DII, energy-adjusted DII (E-DII (TM)), and the children's DII (C-DII (TM)) and many chronic NCDs including obesity and cardiometabolic diseases. Although a previous narrative review published in 2019 briefly summarized the evidence in this area, there was a significant increase in papers on this topic since 2020. Therefore, the purpose of this narrative review is to provide an in-depth updated review by including all papers until July 2021 on DII and its relationship with obesity, T2DM, and CVD. Furthermore, we aim to identify potential gaps in the literature and provide future directions for research. Most studies found that DII was associated with an increased risk of obesity, T2DM, and CVD with some relationships being sex-specific. However, we identified the paucity of papers describing associations between dietary inflammation and T2DM and its risk factors. Few studies used gold-standard measures of cardiometabolic risk factors. We also identified the lack of interventional studies designed to change the inflammatory potential of diets and study its effect on cardiometabolic risk factors and diseases. We recommend that such interventional studies are needed to assess if changes in DII, representing the inflammatory potential of diet, independently of changes in body composition can modulate cardiometabolic risk factors and diseases.
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