Shape determination in Bacillus subtilis

被引:48
作者
Carballido-Lopez, Rut [1 ]
Formstone, Alex [2 ]
机构
[1] INRA, Genet Microbienne, F-78352 Jouy En Josas, France
[2] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England
关键词
D O I
10.1016/j.mib.2007.09.008
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The discovery of cytoskeletal elements in prokaryotes has dramatically changed the way we think about bacterial cell morphogenesis. The rod shape of Bacillus subtilis is maintained by the two major polymers (peptidoglycan and teichoic acids) of its thick cell wall and determined by the way these are inserted during growth. The current view is that the dynamic tubulin-like (FtsZ) and actin-like (MreB) cytoskeletons orchestrate, both in time and space, the assembly of macromolecular machineries that effect cell wall synthesis and hydrolysis during cell division and cell elongation, respectively.
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页码:611 / 616
页数:6
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