Double heteroannulation reactions of 1-naphthol with alkyl- and arylmethylidene derivatives of malononitrile dimer

被引:24
作者
Bardasov, Ivan N. [1 ]
Alekseeva, Anastasiya U. [1 ]
Mihailov, Denis L. [1 ]
Ershov, Oleg V. [1 ]
Grishanov, Dmitry A. [2 ]
机构
[1] Ulyanov Chuvash State Univ, Cheboksaly 428015, Russia
[2] Russian Acad Sci, Kumakov Inst Gen & Inorgan Chem, Moscow 119991, Russia
关键词
Heterocyclic compounds; Cyano compounds; One-pot reactions; Pyran; Double heteroannulation reactions; Michael addition; IN-VITRO EVALUATION; MIRC REACTIONS; INHIBITORS; NITRILES;
D O I
10.1016/j.tetlet.2015.02.081
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of 7H-benzo[7,8]chromeno[2,3-b]pyridine derivatives from the reactions of arylmethylidene derivatives of malononitrile dimer with 1-naphthol is described. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1830 / 1832
页数:3
相关论文
共 29 条
[1]  
Alekseeva A. Yu., 2013, RUSS J ORG CHEM+, V49, P1715
[2]  
Alekseeva A. Yu., 2014, RUSS J ORG CHEM+, V50, P244
[3]   Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2) [J].
Anderson, DR ;
Hegde, S ;
Reinhard, E ;
Gomez, L ;
Vernier, WF ;
Lee, L ;
Liu, S ;
Sambandam, A ;
Snider, PA ;
Masih, L .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (06) :1587-1590
[4]   One-pot synthesis of 2-(dicyanomethylene)-1,2-dihydropyridine derivatives [J].
Bardasov, Ivan N. ;
Alekseeva, Anastasiya U. ;
Mihailov, Denis L. ;
Ershov, Oleg V. ;
Nasakin, Oleg E. ;
Tafeenko, Viktor A. .
TETRAHEDRON LETTERS, 2014, 55 (16) :2730-2733
[5]   Highly-substituted pyrazoles and pyridazines by MIRC reactions of hydrazone anions and nitrobutadienic fragments [J].
Bianchi, Lara ;
Carloni-Garaventa, Alessandro ;
Maccagno, Massimo ;
Petrillo, Giovanni ;
Scapolla, Carlo ;
Tavani, Cinzia .
TETRAHEDRON LETTERS, 2012, 53 (47) :6394-6400
[6]   Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38αMAPK inhibitors in Werner syndrome cells [J].
Davis, Terence ;
Bagley, Mark C. ;
Dix, Matthew C. ;
Murziani, Paola G. S. ;
Rokicki, Michal J. ;
Widdowson, Caroline S. ;
Zayed, Jameel M. ;
Bachler, Marcus A. ;
Kipling, David .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (24) :6832-6835
[7]   Studies on the synthesis, in vitro antitumor activity of 4H-benzo[h]chromene, 7H-benzo[h]chromene[2,3-d]pyrimidine derivatives and structure-activity relationships of the 2-,3-and 2,3-positions [J].
El-Agrody, Ahmed M. ;
Fouda, Ahmed M. ;
Al-Dies, Al-Anood M. .
MEDICINAL CHEMISTRY RESEARCH, 2014, 23 (06) :3187-3199
[8]   Synthesis, antitumor activity of 2-amino-4H-benzo[h]chromene derivatives, and structure-activity relationships of the 3-and 4-positions [J].
El-Agrody, Ahmed M. ;
Fouda, Ahmed M. ;
Khattab, Essam Shawky A. E. H. .
MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (12) :6105-6120
[9]  
El-Agrody AM., 2014, Eur. J. Chem, V5, P133, DOI [10.5155/eurjchem.5.1.133-137.923, DOI 10.5155/EURJCHEM.5.1.133-137.923]
[10]   NITRILES IN HETEROCYCLIC SYNTHESIS - A NOVEL ROUTE FOR THE SYNTHESIS OF NAPHTHODIPYRANS, PYRIDINES - 2H-PYRANS AND 4H-PYRANS [J].
ELAGAMEY, AGA ;
ELTAWEEL, FMA ;
SOWELLIM, SZA ;
SOFAN, MA ;
ELNAGDI, MH .
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1990, 55 (02) :524-534