Scaffolding H2O2 signaling

被引：5
作者：
Sikes, Hadley D. [1 ]
机构：
[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA
来源：
NATURE CHEMICAL BIOLOGY | 2017年 / 13卷 / 08期
关键词：
PEROXIDE-INDUCED OXIDATION; TRANSCRIPTION FACTOR; YBP1; YAP1;
D O I：
10.1038/nchembio.2432
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Peroxidases, rather than simply reducing H2O2 to water, also convey oxidation signals to proteins such as transcription factors. A new study reveals how a scaffold protein enables formation of a mixed disulfide between the peroxidase and a transcription factor.
引用
收藏
页码：818 / 819
页数：2
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